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Publications

Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy.

Leylek O, Honeywell ME, Lee MJ, Hemann MT, Ozcan G. Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.07.561351

circulating tumor DNA in the immediate post-operative setting.

Efthymiou V, Queenan N, Haas M, Naegele S, Goss D, Faden DL. circulating tumor DNA in the immediate post-operative setting. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.09.30.23296390

Prior Sexual Trauma Exposure Impacts Posttraumatic Dysfunction and Neural Circuitry Following a Recent Traumatic Event in the AURORA Study.

Rowland GE, Roeckner A, Ely TD, et al. Prior Sexual Trauma Exposure Impacts Posttraumatic Dysfunction and Neural Circuitry Following a Recent Traumatic Event in the AURORA Study. Biological psychiatry global open science. 2023;3(4):705-715. doi:10.1016/j.bpsgos.2023.02.004

Youth Team Sports Participation Associates With Reduced Dimensional Psychopathology Through Interaction With Biological Risk Factors.

Kunitoki K, Hughes D, Elyounssi S, et al. Youth Team Sports Participation Associates With Reduced Dimensional Psychopathology Through Interaction With Biological Risk Factors. Biological psychiatry global open science. 2023;3(4):875-883. doi:10.1016/j.bpsgos.2023.02.001

Genetic Predisposition to Elevated C-reactive Protein and Risk of Obstructive Sleep Apnea.

Huang T, Goodman M, Wang H, et al. Genetic Predisposition to Elevated C-reactive Protein and Risk of Obstructive Sleep Apnea. American journal of respiratory and critical care medicine. 2023. doi:10.1164/rccm.202307-1159LE

Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen.

Doss-Gollin S, Thomas S, Brook B, et al. Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen. NPJ vaccines. 2023;8(1):163. doi:10.1038/s41541-023-00759-y

Clonal haematopoiesis, ageing and kidney disease.

Vlasschaert C, Lanktree MB, Rauh MJ, Kelly TN, Natarajan P. Clonal haematopoiesis, ageing and kidney disease. Nature reviews. Nephrology. 2023. doi:10.1038/s41581-023-00778-x

Targeting ROS production through inhibition of NADPH oxidases.

Reis J, Gorgulla C, Massari M, et al. Targeting ROS production through inhibition of NADPH oxidases. Nature chemical biology. 2023;19(12):1540-1550. doi:10.1038/s41589-023-01457-5

Pan-genome de Bruijn graph using the bidirectional FM-index.

Depuydt L, Renders L, Abeel T, Fostier J. Pan-genome de Bruijn graph using the bidirectional FM-index. BMC bioinformatics. 2023;24(1):400. doi:10.1186/s12859-023-05531-6

Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.

Smith K, Deutsch AJ, McGrail C, et al. Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity. Research square. 2023. doi:10.21203/rs.3.rs-3399145/v1