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Publications

Circadian Transcriptome Oscillations In Human Adipose Tissue Depend On Napping Status And Link To Metabolic And Inflammatory Pathways.

Rodríguez-Martín M, Pérez-Sanz F, Zambrano C, et al. Circadian Transcriptome Oscillations In Human Adipose Tissue Depend On Napping Status And Link To Metabolic And Inflammatory Pathways. Sleep. 2024. doi:10.1093/sleep/zsae160

A multi-biomarker micronucleus assay using imaging flow cytometry.

Harte DSG, Lynch AM, Verma J, et al. A multi-biomarker micronucleus assay using imaging flow cytometry. Archives of toxicology. 2024. doi:10.1007/s00204-024-03801-7

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity.

Wu MJ, Kondo H, Kammula A V, et al. Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.). 2024;385(6705):eadl6173. doi:10.1126/science.adl6173

Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records.

Venkatesh SS, Ganjgahi H, Palmer DS, et al. Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records. Nature communications. 2024;15(1):5801. doi:10.1038/s41467-024-49998-0

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing.

Reedy JL, Jensen KN, Crossen AJ, et al. Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing. Nature communications. 2024;15(1):5817. doi:10.1038/s41467-024-50100-x

Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein.

Birkholz N, Kamata K, Feussner M, et al. Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature. 2024. doi:10.1038/s41586-024-07644-1

Single-cell atlas of the human brain vasculature across development, adulthood and disease.

Wälchli T, Ghobrial M, Schwab M, et al. Single-cell atlas of the human brain vasculature across development, adulthood and disease. Nature. 2024. doi:10.1038/s41586-024-07493-y

Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells.

Sousa AA, Hemez C, Lei L, et al. Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells. Nature biomedical engineering. 2024. doi:10.1038/s41551-024-01233-3

IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.

Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J. IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(29):e2404349121. doi:10.1073/pnas.2404349121

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias.

Vedula RS, Karp HQ, Koob J, et al. CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias. Blood. 2024. doi:10.1182/blood.2023022908