ӳ��ý

Publications

Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity.

Zuppi M, Vatanen T, Wilson BC, et al. Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity. Microbiome. 2024;12(1):122. doi:10.1186/s40168-024-01833-w

Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice.

Lee J, Wellenstein K, Rahnavard A, et al. Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(28):e2318691121. doi:10.1073/pnas.2318691121

Histone demethylation tones down leukemia through innate immunity.

Monteleone A, Griffin GK. Histone demethylation tones down leukemia through innate immunity. Science immunology. 2024;9(97):eadr2967. doi:10.1126/sciimmunol.adr2967

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation.

Carey CE, Shafee R, Wedow R, et al. Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation. Nature human behaviour. 2024. doi:10.1038/s41562-024-01909-5

Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1.

Lee K, Barone M, Waterbury AL, et al. Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology. 2024. doi:10.1038/s41589-024-01671-9

Systematic comparison of sequencing-based spatial transcriptomic methods.

You Y, Fu Y, Li L, et al. Systematic comparison of sequencing-based spatial transcriptomic methods. Nature methods. 2024. doi:10.1038/s41592-024-02325-3

AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys.

Liang SQ, Navia AW, Ramseier M, et al. AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. Human gene therapy. 2024. doi:10.1089/hum.2024.035

Targeting IL-1 controls refractory pityriasis rubra pilaris.

Schmauch E, Severin Y, Xing X, et al. Targeting IL-1 controls refractory pityriasis rubra pilaris. Science advances. 2024;10(27):eado2365. doi:10.1126/sciadv.ado2365

From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation.

Soni D, Borriello F, Scott DA, et al. From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation. Science advances. 2024;10(27):eadg3747. doi:10.1126/sciadv.adg3747

Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities.

Kim MS, Shim I, Fahed AC, et al. Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities. Cell metabolism. 2024;36(7):1494-1503.e3. doi:10.1016/j.cmet.2024.06.004