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Publications

Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease.

Khrom M, Long M, Dube S, et al. Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease. Gastroenterology. 2024. doi:10.1053/j.gastro.2024.02.026

Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.

Brandt M, Cao Z, Krishna C, et al. Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses. Cell reports. 2024;43(3):113944. doi:10.1016/j.celrep.2024.113944

CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.

Qin X, Lam A, Zhang X, et al. CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness. Science advances. 2024;10(11):eadh9547. doi:10.1126/sciadv.adh9547

Treating Hypertension: Important for Heart Health, Fundamental for Brain Health.

Singh SD, Senff JR, van Duijn CM, Rosand J. Treating Hypertension: Important for Heart Health, Fundamental for Brain Health. Stroke. 2024. doi:10.1161/STROKEAHA.123.046179

Assessing the impact of post-mortem damage and contamination on imputation performance in ancient DNA.

Marques AG, Rubinacci S, Malaspinas AS, Delaneau O, da Mota BS. Assessing the impact of post-mortem damage and contamination on imputation performance in ancient DNA. Scientific reports. 2024;14(1):6227. doi:10.1038/s41598-024-56584-3

In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies.

Yin Y, Guo Y, Jiang Y, et al. In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies. Nature biomedical engineering. 2024. doi:10.1038/s41551-024-01179-6

A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.

Hwang GH, Pazyra-Murphy MF, Seo HS, et al. A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer research. 2024;84(6):872-886. doi:10.1158/0008-5472.CAN-22-3784

Long-Term Outcomes in Patients With Spontaneous Cerebellar Hemorrhage: An International Cohort Study.

Senff JR, Singh SD, Pasi M, et al. Long-Term Outcomes in Patients With Spontaneous Cerebellar Hemorrhage: An International Cohort Study. Stroke. 2024. doi:10.1161/STROKEAHA.123.044622

Modular vector assembly enables rapid assessment of emerging CRISPR technologies.

McGee A V, Liu Y V, Griffith AL, et al. Modular vector assembly enables rapid assessment of emerging CRISPR technologies. Cell genomics. 2024;4(3):100519. doi:10.1016/j.xgen.2024.100519

Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities.

Li Y, Hong X, Chandran A, et al. Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024. doi:10.1016/j.anai.2024.03.001