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Publications

Integrated annotation prioritizes metabolites with bioactivity in inflammatory bowel disease.

Bhosle A, Bae S, Zhang Y, et al. Integrated annotation prioritizes metabolites with bioactivity in inflammatory bowel disease. Molecular systems biology. 2024. doi:10.1038/s44320-024-00027-8

A recurrent missense variant in the E3 ubiquitin ligase substrate recognition subunit FEM1B causes a rare syndromic neurodevelopmental disorder.

Lecoquierre F, Punt M, Ebstein F, et al. A recurrent missense variant in the E3 ubiquitin ligase substrate recognition subunit FEM1B causes a rare syndromic neurodevelopmental disorder. Genetics in medicine : official journal of the American College of Medical Genetics. 2024:101119. doi:10.1016/j.gim.2024.101119

Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB dependent IFITM3 expression.

Munir M, Embry A, Doench JG, Heaton NS, Wilen CB, Orchard RC. Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB dependent IFITM3 expression. The Journal of biological chemistry. 2024:107153. doi:10.1016/j.jbc.2024.107153

Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma.

Mendez KM, Begum S, Tiwari A, et al. Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma. EBioMedicine. 2024;102:105025. doi:10.1016/j.ebiom.2024.105025

Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development.

Kim T, Martínez-Bonet M, Wang Q, et al. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nature communications. 2024;15(1):2150. doi:10.1038/s41467-024-46457-8

Treating insomnia with 40 Hz light flicker.

Bozzelli L, Tsai LH. Treating insomnia with 40 Hz light flicker. Cell research. 2024. doi:10.1038/s41422-024-00948-x

Publisher Correction: Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis.

Dashti HS, Scheer FAJL, Saxena R, Garaulet M. Publisher Correction: Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis. International journal of obesity (2005). 2024. doi:10.1038/s41366-024-01497-4

Mendelian randomization analysis using multiple biomarkers of an underlying common exposure.

Jin J, Qi G, Yu Z, Chatterjee N. Mendelian randomization analysis using multiple biomarkers of an underlying common exposure. Biostatistics (Oxford, England). 2024. doi:10.1093/biostatistics/kxae006

Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases.

Yin Z, Klionsky DJ. Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases. Autophagy. 2024:1-2. doi:10.1080/15548627.2024.2323294

Graph Fourier transform for spatial omics representation and analyses of complex organs.

Chang Y, Liu J, Jiang Y, et al. Graph Fourier transform for spatial omics representation and analyses of complex organs. Research square. 2024. doi:10.21203/rs.3.rs-3952048/v1