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Publications

Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells.

Lackey EP, Moreira L, Norton A, et al. Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells. Neuron. 2024. doi:10.1016/j.neuron.2024.04.010

Genetic dependencies associated with transcription factor activities in human cancer cell lines.

Thatikonda V, Supper V, Wachter J, et al. Genetic dependencies associated with transcription factor activities in human cancer cell lines. Cell reports. 2024;43(5):114175. doi:10.1016/j.celrep.2024.114175

Biophysical characterization of high-confidence, small human proteins.

Whited AM, Jungreis I, Allen J, et al. Biophysical characterization of high-confidence, small human proteins. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.04.12.589296

Robust self-supervised denoising of voltage imaging data using CellMincer.

Wang B, Ma T, Chen T, et al. Robust self-supervised denoising of voltage imaging data using CellMincer. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.04.12.589298

Author Correction: Specific heterozygous variants in MGP lead to endoplasmic reticulum stress and cause spondyloepiphyseal dysplasia.

Gourgas O, Lemire G, Eaton AJ, et al. Author Correction: Specific heterozygous variants in MGP lead to endoplasmic reticulum stress and cause spondyloepiphyseal dysplasia. Nature communications. 2024;15(1):3655. doi:10.1038/s41467-024-47898-x

Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries.

Zheng Z, Liu S, Sidorenko J, et al. Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature genetics. 2024. doi:10.1038/s41588-024-01704-y

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, et al. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature genetics. 2024. doi:10.1038/s41588-024-01714-w

Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network.

Lewis ACF, Chisholm RL, Connolly JJ, et al. Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.04.005

Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.

Senkpeil L, Bhardwaj J, Little MR, et al. Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine. JCI insight. 2024. doi:10.1172/jci.insight.167408

Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings.

Berger AG, DeLorenzo C, Vo C, Kaskow JA, Nabar N, Hammond PT. Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings. Biomacromolecules. 2024. doi:10.1021/acs.biomac.4c00062