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Publications

Diet and gut microbial associations in irritable bowel syndrome according to disease subtype.

Wang Y, Ma W, Mehta R, et al. Diet and gut microbial associations in irritable bowel syndrome according to disease subtype. Gut microbes. 2023;15(2):2262130. doi:10.1080/19490976.2023.2262130

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations.

Thomas M, Su YR, Rosenthal EA, et al. Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nature communications. 2023;14(1):6147. doi:10.1038/s41467-023-41819-0

Challenges and opportunities in sharing microbiome data and analyses.

Huttenhower C, Finn RD, McHardy AC. Challenges and opportunities in sharing microbiome data and analyses. Nature microbiology. 2023. doi:10.1038/s41564-023-01484-x

Assigning functionality to cysteines by base editing of cancer dependency genes.

Li H, Ma T, Remsberg JR, et al. Assigning functionality to cysteines by base editing of cancer dependency genes. Nature chemical biology. 2023. doi:10.1038/s41589-023-01428-w

Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy.

Kabra M, Shahi PK, Wang Y, et al. Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy. The Journal of clinical investigation. 2023;133(19). doi:10.1172/JCI171356

Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity.

Chitraju C, Fischer AW, Ambaw YA, et al. Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity. eLife. 2023;12. doi:10.7554/eLife.88049

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Nyman J, Denize T, Bakouny Z, et al. Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.01.18.524545

Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer.

Hermida-Prado F, Xie Y, Sherman S, et al. Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer. Cancer research. 2023;83(19):3284-3304. doi:10.1158/0008-5472.CAN-23-1711

Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells.

Truex NL, Rondon A, Rössler SL, et al. Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells. ACS central science. 2023;9(9):1835-1845. doi:10.1021/acscentsci.3c00625

CD11a regulates hematopoietic stem and progenitor cells.

Hou L, Yuki K. CD11a regulates hematopoietic stem and progenitor cells. Frontiers in immunology. 2023;14:1219953. doi:10.3389/fimmu.2023.1219953