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Publications

Complex Regulatory Interactions at GDF5 Shape Joint Morphology and Osteoarthritis Disease Risk.

Coveney CR, Maridas D, Chen H, et al. Complex Regulatory Interactions at GDF5 Shape Joint Morphology and Osteoarthritis Disease Risk. Arthritis & rheumatology (Hoboken, N.J.). 2025. doi:10.1002/art.43231

Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases.

Tavora R, Zhang L, Tran MH, et al. Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases. Human gene therapy. 2025;36(11-12):870-883. doi:10.1089/hum.2025.011

Data-driven consideration of genetic disorders for global genomic newborn screening programs.

Minten T, Bick S, Adelson S, et al. Data-driven consideration of genetic disorders for global genomic newborn screening programs. Genetics in medicine : official journal of the American College of Medical Genetics. 2025;27(7):101443. doi:10.1016/j.gim.2025.101443

Chemotherapy and the somatic mutation burden of sperm.

Picciotto S, Arenas-Gallo C, Toren A, et al. Chemotherapy and the somatic mutation burden of sperm. JCI insight. 2025;10(12). doi:10.1172/jci.insight.188175

Bidirectional associations of zinc supplement intake with biological ageing interacted by metabolic equivalent of task: A large-scale population-based Biobank study.

Zhou Y, Zhou J, Li Z, et al. Bidirectional associations of zinc supplement intake with biological ageing interacted by metabolic equivalent of task: A large-scale population-based Biobank study. Clinical nutrition (Edinburgh, Scotland). 2025;50:1-9. doi:10.1016/j.clnu.2025.04.029

Harmonizing TUNEL with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death.

Sherman MS, McMahon-Skates T, Gaston LS, Katzen SW, Majzoub JA, Goessling W. Harmonizing TUNEL with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death. Cell reports methods. 2025;5(5):101047. doi:10.1016/j.crmeth.2025.101047

Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.

Loft A, Emont MP, Weinstock A, et al. Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution. Nature metabolism. 2025;7(5):875-894. doi:10.1038/s42255-025-01296-9

Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice.

Kwon DI, Mao T, Israelow B, de Sá KSG, Dong H, Iwasaki A. Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice. Nature immunology. 2025;26(6):908-919. doi:10.1038/s41590-025-02156-0

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.

Strom NI, Gerring ZF, Galimberti M, et al. Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder. Nature genetics. 2025;57(6):1389-1401. doi:10.1038/s41588-025-02189-z

Prediction of protein subcellular localization in single cells.

Zhang X, Tseo Y, Bai Y, Chen F, Uhler C. Prediction of protein subcellular localization in single cells. Nature methods. 2025;22(6):1265-1275. doi:10.1038/s41592-025-02696-1