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Proteome-wide model for human disease genetics. Orenbuch R, Shearer CA, Kollasch AW, et al. Proteome-wide model for human disease genetics. Nature genetics. 2025. doi:10.1038/s41588-025-02400-1 Read more
Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks. Sui X, Lo JA, Luo S, et al. Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks. Nature methods. 2025. doi:10.1038/s41592-025-02867-0 Read more
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis. Minetti A, Omrani O, Brenner C, et al. Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis. Nature cell biology. 2025. doi:10.1038/s41556-025-01804-9 Read more
Solving the where problem and quantifying geometric variation in neuroanatomy using generative diffeomorphic mapping. Tward DJ, Gray BDP, Li X, et al. Solving the where problem and quantifying geometric variation in neuroanatomy using generative diffeomorphic mapping. Nature communications. 2025;16(1):10398. doi:10.1038/s41467-025-65317-7 Read more
Integrating extensive functional annotations and multiomics of cattle enhances climate resilience prediction and mapping. Xiang R, Breen E, Bolormaa S, et al. Integrating extensive functional annotations and multiomics of cattle enhances climate resilience prediction and mapping. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(49):e2514736122. doi:10.1073/pnas.2514736122 Read more
Genomic ancestry, behavior, and the domestication of the dog. Lord KA, Larson G, Murphy WJ, Ostrander EA. Genomic ancestry, behavior, and the domestication of the dog. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(48):e2528616122. doi:10.1073/pnas.2528616122 Read more
Genetic testing predicts appearance but not behavior in dogs. Lord KA, Sohrab V, Bryc K, et al. Genetic testing predicts appearance but not behavior in dogs. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(48):e2421752122. doi:10.1073/pnas.2421752122 Read more
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Genome duplication in a long-term multicellularity evolution experiment. Tong K, Datta S, Cheng V, et al. Genome duplication in a long-term multicellularity evolution experiment. Nature. 2025;639(8055):691-699. doi:10.1038/s41586-025-08689-6 PMCID PMC12256070 Read more