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Publications

Generalizable AI predicts immunotherapy outcomes across cancers and treatments.

Shen W, Nguyen TH, Li MM, et al. Generalizable AI predicts immunotherapy outcomes across cancers and treatments. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.01.25326820

Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissues.

Bocher O, Arruda AL, Yoshiji S, et al. Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissues. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.05.25326880

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities.

Arruda AL, Bocher O, Taylor HJ, et al. The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.05.25326966

Androgens mediate sexual dimorphism in Pilarowski-Bjornsson Syndrome.

Anderson KJ, Thorolfsdottir ET, Nodelman IM, et al. Androgens mediate sexual dimorphism in Pilarowski-Bjornsson Syndrome. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.06.25326635

Genomics reveals zoonotic and sustained human mpox spread in West Africa.

Parker E, Omah IF, Djuicy DD, et al. Genomics reveals zoonotic and sustained human mpox spread in West Africa. Nature. 2025;643(8074):1343-1351. doi:10.1038/s41586-025-09128-2

The contribution of gametic phase disequilibrium to the heritability of complex traits.

Zhang Y, Sakaue S, Morris S, et al. The contribution of gametic phase disequilibrium to the heritability of complex traits. Nature genetics. 2025;57(6):1418-1425. doi:10.1038/s41588-025-02192-4

Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes.

Murthy VL, Piaggi P, Lin P, et al. Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes. Diabetes care. 2025;48(7):1260-1272. doi:10.2337/dc25-0151

Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage.

Braun F, Mandel AM, Blomberg L, et al. Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage. JCI insight. 2025;10(12). doi:10.1172/jci.insight.172370

Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.

Beccari MS, Arnold-Garcia O, Baughn MW, et al. Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(21):e2502294122. doi:10.1073/pnas.2502294122

Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care.

Kreienkamp RJ, Deutsch AJ, Huerta-Chagoya A, et al. Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care. Hormone research in paediatrics. 2025:1-9. doi:10.1159/000546445