A chemical-genetic interaction between PAF1 and ENL/AF9 YEATS inhibition. Barta P, Garnar-Wortzel L, Bishop T, et al. A chemical-genetic interaction between PAF1 and ENL/AF9 YEATS inhibition. RSC chemical biology. 2025. doi:10.1039/d5cb00233h PMCID PMC12550596 Read more
Dissecting the Predictive Accuracy of Polygenic Indexes for Behavioral Phenotypes Across Genetic Ancestries. Alemu R, Young AS, Benjamin DJ, Turley P, Okbay A. Dissecting the Predictive Accuracy of Polygenic Indexes for Behavioral Phenotypes Across Genetic Ancestries. Research square. 2025. doi:10.21203/rs.3.rs-7584560/v1 PMCID PMC12622163 Read more
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV. Liao H, Conwill A, Light-Maka I, et al. High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.26.678787 PMCID PMC12622049 Read more
A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma. Deng EB, Zhong X, Xin D, et al. A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.29.679095 PMCID PMC12621713 Read more
Segregating DNA lesions point to high selective advantage of tumor initiating cells. Seplyarskiy V, Shady M, Andrianova MA, Chapman MS, Van Allen EM, Sunyaev SR. Segregating DNA lesions point to high selective advantage of tumor initiating cells. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.02.680094 PMCID PMC12621763 Read more
Developing a general AI model for integrating diverse genomic modalities and comprehensive genomic knowledge. Zhang Z, Bao X, Jiang L, et al. Developing a general AI model for integrating diverse genomic modalities and comprehensive genomic knowledge. Nucleic acids research. 2025;53(21). doi:10.1093/nar/gkaf1269 Read more
A Lack of Information About Family Health History Motivates Adopted Individuals to Pursue Elective Genomic Testing. Hickingbotham MR, Bell M, Zoltick ES, et al. A Lack of Information About Family Health History Motivates Adopted Individuals to Pursue Elective Genomic Testing. American journal of medical genetics. Part A. 2025:e70005. doi:10.1002/ajmga.70005 Read more
Leveraging a Genetic Proxy to Investigate the Effects of Lifelong Cardiac Sodium Channel Blockade. Wanner JS, Krafft M, Niiranen T, et al. Leveraging a Genetic Proxy to Investigate the Effects of Lifelong Cardiac Sodium Channel Blockade. Circulation. 2025. doi:10.1161/CIRCULATIONAHA.125.075057 Read more
Disparities in immunotherapy treatment for mycosis fungoides and Sézary syndrome in the National Cancer Database. Peacker BL, Thompson BB, Behbahani S, et al. Disparities in immunotherapy treatment for mycosis fungoides and Sézary syndrome in the National Cancer Database. Journal of the American Academy of Dermatology. 2025. doi:10.1016/j.jaad.2025.11.052 Read more
Predictive value of maximum tumor dissemination (Dmax) in lymphoma patients treated with CD19-specific CAR T-Cells. Winkelmann M, Achhammer P, Blumenberg V, et al. Predictive value of maximum tumor dissemination (Dmax) in lymphoma patients treated with CD19-specific CAR T-Cells. Cancer imaging : the official publication of the International Cancer Imaging Society. 2025. doi:10.1186/s40644-025-00959-w Read more