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Publications

The genetic basis of autoimmunity seen through the lens of T cell functional traits.

Lagattuta KA, Park HL, Rumker L, Ishigaki K, Nathan A, Raychaudhuri S. The genetic basis of autoimmunity seen through the lens of T cell functional traits. Nature communications. 2024;15(1):1204. doi:10.1038/s41467-024-45170-w

Medieval DNA from Soqotra points to Eurasian origins of an isolated population at the crossroads of Africa and Arabia.

Sirak K, Van Rensburg JJ, Brielle E, et al. Medieval DNA from Soqotra points to Eurasian origins of an isolated population at the crossroads of Africa and Arabia. Nature ecology & evolution. 2024. doi:10.1038/s41559-024-02322-x

The single-cell transcriptome program of nodule development cellular lineages in Medicago truncatula.

Pereira WJ, Boyd J, Conde D, et al. The single-cell transcriptome program of nodule development cellular lineages in Medicago truncatula. Cell reports. 2024;43(2):113747. doi:10.1016/j.celrep.2024.113747

Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase.

Maw JJ, Coker JA, Arya T, et al. Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase. Journal of medicinal chemistry. 2024. doi:10.1021/acs.jmedchem.3c01807

Mitochondrial dysfunction in Spaceflight Associated Neuro-Ocular Syndrome (SANS): a molecular hypothesis in pathogenesis.

Waisberg E, Ong J, Masalkhi M, Mao XW, Beheshti A, Lee AG. Mitochondrial dysfunction in Spaceflight Associated Neuro-Ocular Syndrome (SANS): a molecular hypothesis in pathogenesis. Eye (London, England). 2024. doi:10.1038/s41433-024-02951-3

Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever.

Kotliar D, Raju S, Tabrizi S, et al. Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever. Nature microbiology. 2024. doi:10.1038/s41564-023-01589-3

Convergence of coronary artery disease genes onto endothelial cell programs.

Schnitzler GR, Kang H, Fang S, et al. Convergence of coronary artery disease genes onto endothelial cell programs. Nature. 2024. doi:10.1038/s41586-024-07022-x

De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors.

Akshay A, Gheinani AH, Besic M, et al. De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors. BMC urology. 2024;24(1):33. doi:10.1186/s12894-024-01417-8

Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges.

Haradhvala NJ, Maus M V. Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges. Blood cancer discovery. 2024:OF1-OF4. doi:10.1158/2643-3230.BCD-23-0212

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1.

Hai L, Hoffmann DC, Wagener RJ, et al. A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1. Nature communications. 2024;15(1):968. doi:10.1038/s41467-024-45067-8