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Publications

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.

Cheong JG, Ravishankar A, Sharma S, et al. Epigenetic memory of coronavirus infection in innate immune cells and their progenitors. Cell. 2023. doi:10.1016/j.cell.2023.07.019

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.

Larange A, Takazawa I, Kakugawa K, et al. A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function. Immunity. 2023. doi:10.1016/j.immuni.2023.07.017

Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors.

Groves A, Ward A, Li YY, et al. Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors. Pediatric blood & cancer. 2023:e30643. doi:10.1002/pbc.30643

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.

Miller PG, Sperling AS, Mayerhofer C, et al. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. 2023. doi:10.1182/blood.2023020331

Systematic evaluation of genome sequencing for the diagnostic assessment of autism spectrum disorder and fetal structural anomalies.

Lowther C, Valkanas E, Giordano JL, et al. Systematic evaluation of genome sequencing for the diagnostic assessment of autism spectrum disorder and fetal structural anomalies. American journal of human genetics. 2023. doi:10.1016/j.ajhg.2023.07.010

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.

O’Meara TR, Nanishi E, McGrath ME, et al. Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance. The Journal of allergy and clinical immunology. 2023. doi:10.1016/j.jaci.2023.06.031

A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.

Akbari P, Vuckovic D, Stefanucci L, et al. A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology. Nature communications. 2023;14(1):5023. doi:10.1038/s41467-023-40679-y

KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.

Duplaquet L, Li Y, Booker MA, et al. KDM6A epigenetically regulates subtype plasticity in small cell lung cancer. Nature cell biology. 2023. doi:10.1038/s41556-023-01210-z

Artificial intelligence for dementia drug discovery and trials optimization.

Doherty T, Yao Z, Khleifat AAL, et al. Artificial intelligence for dementia drug discovery and trials optimization. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2023. doi:10.1002/alz.13428

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.

Martell DJ, Merens HE, Caulier A, et al. RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation. Developmental cell. 2023. doi:10.1016/j.devcel.2023.07.018