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Publications

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.

Wieder N, Fried JC, Kim C, et al. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.19.529127

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice.

Everette KA, Newby GA, Levine RM, et al. Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice. Nature biomedical engineering. 2023. doi:10.1038/s41551-023-01026-0

Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer.

Ravi A, Hellmann MD, Arniella MB, et al. Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer. Nature genetics. 2023. doi:10.1038/s41588-023-01355-5

LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.

Sato S, Gillette M, de Santiago P, et al. LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma. Scientific reports. 2023;13(1):1537. doi:10.1038/s41598-023-28840-5

ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.

Gentili M, Liu B, Papanastasiou M, et al. ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling. Nature communications. 2023;14(1):611. doi:10.1038/s41467-023-36132-9

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu W, Cheah J, Xu C, et al. Dynamic mapping of proteome trafficking within and between living cells by TransitID. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.07.527548

Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.

Lee SY, Cheah JS, Zhao B, et al. Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.09.531939

Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry.

Phulphagar KM, Ctortecka C, Jacome ASV, et al. Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.10.532106

Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Abelin J, Bergstrom E, Rivera K, et al. Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues. Nature communications. 2023;14(1):1851. doi:10.1038/s41467-023-37547-0

Programmable protein delivery with a bacterial contractile injection system.

Kreitz J, Friedrich M, Guru A, et al. Programmable protein delivery with a bacterial contractile injection system. Nature. 2023. doi:10.1038/s41586-023-05870-7