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Publications

A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses.

Cohen KW, De Rosa SC, Fulp WJ, et al. A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses. Science translational medicine. 2023;15(697):eadf3309. doi:10.1126/scitranslmed.adf3309

Deep integrative models for large-scale human genomics.

Sigurdsson AI, Louloudis I, Banasik K, et al. Deep integrative models for large-scale human genomics. Nucleic acids research. 2023. doi:10.1093/nar/gkad373

Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts.

Giannuzzi G, Chatron N, Mannik K, et al. Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts. NPJ genomic medicine. 2023;8(1):9. doi:10.1038/s41525-023-00354-z

Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study.

McCabe SD, Hammershaimb A, Cheng D, et al. Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study. Scientific reports. 2023;13(1):8360. doi:10.1038/s41598-023-34340-3

Impact of selection bias on polygenic risk score estimates in healthcare settings.

Lee YH, Thaweethai T, Sheu YH, et al. Impact of selection bias on polygenic risk score estimates in healthcare settings. Psychological medicine. 2023:1-11. doi:10.1017/S0033291723001186

Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam.

Sephton-Clark P, Nguyen T, Hoa NT, et al. Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam. Genetics. 2023. doi:10.1093/genetics/iyad100

Genome-wide CRISPR screening of chondrocyte maturation newly implicates genes in skeletal growth and height-associated GWAS loci.

Baronas JM, Bartell E, Eliasen A, et al. Genome-wide CRISPR screening of chondrocyte maturation newly implicates genes in skeletal growth and height-associated GWAS loci. Cell genomics. 2023;3(5):100299. doi:10.1016/j.xgen.2023.100299

The impact of rare protein coding genetic variation on adult cognitive function.

Chen CY, Tian R, Ge T, et al. The impact of rare protein coding genetic variation on adult cognitive function. Nature genetics. 2023. doi:10.1038/s41588-023-01398-8

Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture.

Kachuri L, C Y Mak A, Hu D, et al. Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture. Nature genetics. 2023. doi:10.1038/s41588-023-01377-z

Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii.

Liu G, Catacutan DB, Rathod K, et al. Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii. Nature chemical biology. 2023. doi:10.1038/s41589-023-01349-8