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Publications

Impact of a negative confirmatory biopsy on risk of disease progression among men on active surveillance for prostate cancer.

Salari K, Kowitz J, Twum-Ampofo J, et al. Impact of a negative confirmatory biopsy on risk of disease progression among men on active surveillance for prostate cancer. Urologic oncology. 2023. doi:10.1016/j.urolonc.2023.04.018

Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank.

Zeleznik OA, Kang JH, Lasky-Su J, et al. Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank. Nature communications. 2023;14(1):2860. doi:10.1038/s41467-023-38466-w

Gene correction for sickle cell disease hits its prime.

Levesque S, Bauer DE. Gene correction for sickle cell disease hits its prime. Nature biomedical engineering. 2023;7(5):605-606. doi:10.1038/s41551-023-01040-2

Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma.

Potter DS, Du R, Bohl SR, et al. Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma. Nature communications. 2023;14(1):2897. doi:10.1038/s41467-023-38552-z

Impact of exposure to per- and polyfluoroalkyl substances on fecal microbiota composition in mother-infant dyads.

Lamichhane S, Härkönen T, Vatanen T, Hyötyläinen T, Knip M, Orešič M. Impact of exposure to per- and polyfluoroalkyl substances on fecal microbiota composition in mother-infant dyads. Environment international. 2023;176:107965. doi:10.1016/j.envint.2023.107965

Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.

Weichert-Leahey N, Shi H, Tao T, et al. Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state. The Journal of clinical investigation. 2023;133(10). doi:10.1172/JCI166919

Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.

Zhang Y, Dron JS, Bellows BK, et al. Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease. Circulation. 2023;147(20):1556-1559. doi:10.1161/CIRCULATIONAHA.123.064168

A single-cell map of antisense oligonucleotide activity in the brain.

Mortberg MA, Gentile JE, Nadaf NM, et al. A single-cell map of antisense oligonucleotide activity in the brain. Nucleic acids research. 2023. doi:10.1093/nar/gkad371

Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan.

Johansen J, Atarashi K, Arai Y, et al. Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan. Nature microbiology. 2023. doi:10.1038/s41564-023-01370-6

Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.

Lee SY, Cheah JS, Zhao B, et al. Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells. Nature methods. 2023. doi:10.1038/s41592-023-01880-5