Byrska-Bishop M, Evani US, Zhao X, et al. High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios. Cell. 2022;185(18):3426-3440.e19. doi:10.1016/j.cell.2022.08.004
Publications
Kummerlowe C, Mwakamui S, Hughes TK, et al. Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation. Sci Transl Med. 2022;14(660):eabi8633. doi:10.1126/scitranslmed.abi8633
Roh W, Geffen Y, Cha H, et al. High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities. Cancer Res. 2022. doi:10.1158/0008-5472.CAN-22-0432
Sazonovs A, Stevens CR, Venkataraman GR, et al. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility. Nat Genet. 2022. doi:10.1038/s41588-022-01156-2
Tye MA, Payne C, Johansson C, et al. Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance. Nat Commun. 2022;13(1):4976. doi:10.1038/s41467-022-32630-4
Fu JM, Satterstrom K, Peng M, et al. Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. Nat Genet. 2022. doi:10.1038/s41588-022-01104-0
Sanidas I, Lee H, Rumde PH, et al. Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression. Mol Cell. 2022. doi:10.1016/j.molcel.2022.07.014
Wong F, Stokes JM, Bening SC, Vidoudez C, Trauger SA, Collins JJ. Reactive metabolic byproducts contribute to antibiotic lethality under anaerobic conditions. Mol Cell. 2022. doi:10.1016/j.molcel.2022.07.009
Stogsdill JA, Kim K, Binan L, Farhi SL, Levin JZ, Arlotta P. Pyramidal neuron subtype diversity governs microglia states in the neocortex. Nature. 2022. doi:10.1038/s41586-022-05056-7
Najjar D, Rainbow J, Timilsina SS, et al. A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma. Nat Biomed Eng. 2022. doi:10.1038/s41551-022-00919-w