Publications

Pan-cancer integrative histology-genomic analysis via multimodal deep learning.

Chen RJ, Lu MY, Williamson DFK, et al. Pan-cancer integrative histology-genomic analysis via multimodal deep learning. Cancer Cell. 2022;40(8):865-878.e6. doi:10.1016/j.ccell.2022.07.004

Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.

Broto M, Kaminski MM, Adrianus C, et al. Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs. Nat Nanotechnol. 2022. doi:10.1038/s41565-022-01179-0

A cross-disorder dosage sensitivity map of the human genome.

Collins RL, Glessner JT, Porcu E, et al. A cross-disorder dosage sensitivity map of the human genome. Cell. 2022;185(16):3041-3055.e25. doi:10.1016/j.cell.2022.06.036

Molecular map of chronic lymphocytic leukemia and its impact on outcome.

Knisbacher BA, Lin Z, Hahn CK, et al. Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nat Genet. 2022. doi:10.1038/s41588-022-01140-w

Transcriptome variation in human tissues revealed by long-read sequencing.

Glinos DA, Garborcauskas G, Hoffman P, et al. Transcriptome variation in human tissues revealed by long-read sequencing. Nature. 2022. doi:10.1038/s41586-022-05035-y

A genetic model for proximity labelling of the mammalian secretome.

Yang R, Meyer AS, Droujinine IA, et al. A genetic model for proximity labelling of the mammalian secretome. Open Biol. 2022;12(8):220149. doi:10.1098/rsob.220149

A first update on mapping the human genetic architecture of COVID-19.

COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19. Nature. 2022;608(7921):E1-E10. doi:10.1038/s41586-022-04826-7

Duration of Symptoms and Association With Positive Home Rapid Antigen Test Results After Infection With SARS-CoV-2.

Cosimi LA, Kelly C, Esposito S, et al. Duration of Symptoms and Association With Positive Home Rapid Antigen Test Results After Infection With SARS-CoV-2. JAMA Netw Open. 2022;5(8):e2225331. doi:10.1001/jamanetworkopen.2022.25331

Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550.

Lee Y, Kim H, Barker D, et al. Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550. Hum Mol Genet. 2022. doi:10.1093/hmg/ddac165

Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.

Kaur G, Porter CBM, Ashenberg O, et al. Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade. Nat Commun. 2022;13(1):4398. doi:10.1038/s41467-022-32171-w