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Publications

Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions.

Ye X, Lee YC, Gates ZP, et al. Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions. Communications chemistry. 2022;5(1):128. doi:10.1038/s42004-022-00737-w

Immune system-wide Mendelian randomization and triangulation analyses support autoimmunity as a modifiable component in dementia-causing diseases.

Lindbohm J V, Mars N, Sipilä PN, et al. Immune system-wide Mendelian randomization and triangulation analyses support autoimmunity as a modifiable component in dementia-causing diseases. Nature aging. 2022;2(10):956-972. doi:10.1038/s43587-022-00293-x

Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.

Zhou W, Kanai M, Wu KHH, et al. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell genomics. 2022;2(10):100192. doi:10.1016/j.xgen.2022.100192

Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics.

Partanen JJ, Häppölä P, Zhou W, et al. Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics. Cell genomics. 2022;2(10):100181. doi:10.1016/j.xgen.2022.100181

The HUNT study: A population-based cohort for genetic research.

Brumpton BM, Graham S, Surakka I, et al. The HUNT study: A population-based cohort for genetic research. Cell genomics. 2022;2(10):100193. doi:10.1016/j.xgen.2022.100193

A practical guideline of genomics-driven drug discovery in the era of global biobank meta-analysis.

Namba S, Konuma T, Wu KH, Zhou W, Initiative GBM analysis, Okada Y. A practical guideline of genomics-driven drug discovery in the era of global biobank meta-analysis. Cell genomics. 2022;2(10):100190. doi:10.1016/j.xgen.2022.100190

In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma.

Lemmel S, weckmann M, Wohlers A, Jirmo A, Carpenter AE. In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma. Front. Pharmacol. 2022.

Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements.

Battaglia S, Dong K, Wu J, et al. Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. Nat Genet. 2022;54(10):1504-1513. doi:10.1038/s41588-022-01188-8

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.

Dubrot J, Du PP, Lane-Reticker SK, et al. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer. Nat Immunol. 2022;23(10):1495-1506. doi:10.1038/s41590-022-01315-x

COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior.

Schimmoller BJ, Trovão NS, Isbell M, et al. COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior. Sci Adv. 2022;8(39):eabq0593. doi:10.1126/sciadv.abq0593