Huang TP, Heins ZJ, Miller SM, et al. High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs. Nat Biotechnol. 2022. doi:10.1038/s41587-022-01410-2
Publications
Guo R, Liang JH, Zhang Y, et al. Methionine metabolism controls the B cell EBV epigenome and viral latency. Cell Metab. 2022;34(9):1280-1297.e9. doi:10.1016/j.cmet.2022.08.008
Susco SG, Ghosh S, Mazzucato P, et al. Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models. Cell Rep. 2022;40(10):111312. doi:10.1016/j.celrep.2022.111312
Halford JL, Morrill VN, Choi SH, et al. Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nature communications. 2022;13(1):5767. doi:10.1038/s41467-022-33534-z
Kartha V, Duarte F, Hu Y, et al. Functional inference of gene regulation using single-cell multi-omics. Cell genomics. 2022;2(9). doi:10.1016/j.xgen.2022.100166
Wang Q, Li H, Tajima K, et al. Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. 2022;609(7925):151-158. doi:10.1038/s41586-022-05067-4
Paranjpe MD, Chaffin M, Zahid S, et al. Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease. PLoS genetics. 2022;18(9):e1010294. doi:10.1371/journal.pgen.1010294
Crowdis J, Balch S, Sterlin L, et al. A patient-driven clinicogenomic partnership for metastatic prostate cancer. Cell genomics. 2022;2(9). doi:10.1016/j.xgen.2022.100169
Uzquiano A, Kedaigle AJ, Pigoni M, et al. Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022;185(20):3770-3788.e27. doi:10.1016/j.cell.2022.09.010
Yao L, D’Agostino GD, Park J, et al. A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria. Nature microbiology. 2022;7(9):1404-1418. doi:10.1038/s41564-022-01176-y