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Publications

Compatibility rules of human enhancer and promoter sequences.

Bergman DT, Jones TR, Liu V, et al. Compatibility rules of human enhancer and promoter sequences. Nature. 2022;607(7917):176-184. doi:10.1038/s41586-022-04877-w

Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery.

Siegenfeld AP, Roseman S, Roh H, et al. Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery. Nature communications. 2022;13(1):4199. doi:10.1038/s41467-022-31857-5

Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins.

Shoba VM, Godage DNPM, Chaudhary SK, Deb A, Siriwardena SU, Choudhary A. Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins. Angewandte Chemie (International ed. in English). 2022;61(29):e202202770. doi:10.1002/anie.202202770

Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes.

Wang F, Baden MY, Guasch-Ferré M, et al. Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes. Diabetologia. 2022;65(7):1119-1132. doi:10.1007/s00125-022-05692-8

Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations.

Shekhar M, Gupta C, Suzuki K, Chan C, Murata T, Singharoy A. Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations. ACS central science. 2022;8(7):915-925. doi:10.1021/acscentsci.1c01599

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.

Lee PC, Klaeger S, Le PM, et al. Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma. J Clin Invest. 2022;132(13). doi:10.1172/JCI151666

Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing.

Austin TR, McHugh CP, Brody JA, et al. Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing. Eur J Epidemiol. 2022;37(7):755-765. doi:10.1007/s10654-022-00888-z

Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers.

Liu YC, Hunter-Anderson R, Cheronet O, et al. Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers. Science. 2022;377(6601):72-79. doi:10.1126/science.abm6536

Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells.

Sellar RS, Sperling AS, Słabicki M, et al. Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells. J Clin Invest. 2022. doi:10.1172/JCI153514

The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.

Nehme R, Pietilainen O, Artomov M, et al. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022;13(1):3690. doi:10.1038/s41467-022-31436-8