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Parker E, Cain B, Hajian B, et al. An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with Efficacy against Drug-Resistant Gram-Negative Infections. ACS central science. 2022;8(8):1145-1158. doi:10.1021/acscentsci.2c00598

Shekhar M, Gupta C, Suzuki K, Chan C, Murata T, Singharoy A. Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations. ACS central science. 2022;8(7):915-925. doi:10.1021/acscentsci.1c01599

Miller P, Sathappa M, Moroco J, et al. Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state. Nature communications. 2022;13(1):3778. doi:10.1038/s41467-022-30463-9

Bondeson D, Mullin-Bernstein Z, Oliver S, et al. Systematic profiling of conditional degron tag technologies for target validation studies. Nature communications. 2022;13(1):5495. doi:10.1038/s41467-022-33246-4

Kwon J, Hajian B, Bian Y, et al. Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature. 2022;609(7926):408-415. doi:10.1038/s41586-022-04928-2

Chandrasekaran SN, Cimini BA, Goodale A, et al. Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations. bioRxiv. 2022. doi:10.1101/2022.01.05.475090

Lemmel S, Weckmann M, Wohlers A, et al. In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma. Front Pharmacol. 2022;13:1021317. doi:10.3389/fphar.2022.1021317

Lemmel S, weckmann M, Wohlers A, Jirmo A, Carpenter AE. In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma. Front. Pharmacol. 2022.

Fernando DM, Gee CT, Griffith EC, et al. Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket. Tuberculosis (Edinb). 2022;132:102157. doi:10.1016/j.tube.2021.102157