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Publications

DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data.

Jerby-Arnon L, Regev A. DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data. Nat Biotechnol. 2022. doi:10.1038/s41587-022-01288-0

A New Image for Cell Sorting.

Filby A, Carpenter AE. A New Image for Cell Sorting. N Engl J Med. 2022;386(18):1755-1758. doi:10.1056/NEJMcibr2200971

Improving polygenic prediction in ancestrally diverse populations.

Ruan Y, Lin YF, Feng YCA, et al. Improving polygenic prediction in ancestrally diverse populations. Nat Genet. 2022. doi:10.1038/s41588-022-01054-7

Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells.

Mouri K, Guo MH, de Boer CG, et al. Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells. Nat Genet. 2022. doi:10.1038/s41588-022-01056-5

Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.

Fass DM, Lewis MC, Ahmad R, et al. Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility. Mol Psychiatry. 2022. doi:10.1038/s41380-022-01557-z

Monogenic and Polygenic Contributions to QTc Prolongation in the Population.

Nauffal V, Morrill VN, Jurgens SJ, et al. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. 2022;145(20):1524-1533. doi:10.1161/CIRCULATIONAHA.121.057261

Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue.

Honecker J, Ruschke S, Seeliger C, et al. Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue. EBioMedicine. 2022;79:104020. doi:10.1016/j.ebiom.2022.104020

Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D.

Chen TK, Coca SG, Estrella MM, et al. Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D. Journal of the American Society of Nephrology : JASN. 2022;33(5):996-1010. doi:10.1681/ASN.2021060735

The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers.

Sarzynski MA, Rice TK, Després JP, et al. The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers. Medicine and science in sports and exercise. 2022;54(5S):S1-S43. doi:10.1249/MSS.0000000000002859

Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program.

Manichaikul A, Lin H, Kang C, et al. Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program. Communications biology. 2022;5(1):362. doi:10.1038/s42003-022-03304-0