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Publications

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

Muus C, Luecken MD, Eraslan G, et al. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021;27(3):546-559. doi:10.1038/s41591-020-01227-z

Transcriptional mediators of treatment resistance in lethal prostate cancer.

He MX, Cuoco MS, Crowdis J, et al. Transcriptional mediators of treatment resistance in lethal prostate cancer. Nat Med. 2021;27(3):426-433. doi:10.1038/s41591-021-01244-6

Dissecting the immunogenomic biology of cancer for biomarker development.

Van Allen EM, Choueiri TK. Dissecting the immunogenomic biology of cancer for biomarker development. Nat Rev Clin Oncol. 2021;18(3):133-134. doi:10.1038/s41571-020-00461-1

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.

Frangieh CJ, Melms JC, Thakore PI, et al. Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion. Nat Genet. 2021;53(3):332-341. doi:10.1038/s41588-021-00779-1

Genomic epidemiology of a Cryptococcus neoformans case cluster in Glasgow, Scotland, 2018.

Farrer RA, Borman AM, Inkster T, Fisher MC, Johnson EM, Cuomo CA. Genomic epidemiology of a Cryptococcus neoformans case cluster in Glasgow, Scotland, 2018. Microb Genom. 2021;7(3). doi:10.1099/mgen.0.000537

Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease.

Sidhom EH, Kim C, Kost-Alimova M, et al. Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease. J Clin Invest. 2021;131(5). doi:10.1172/JCI141380

Characterization of the GABRB2-Associated Neurodevelopmental Disorders.

Achkar CME, Harrer M, Smith L, et al. Characterization of the GABRB2-Associated Neurodevelopmental Disorders. Ann Neurol. 2021;89(3):573-586. doi:10.1002/ana.25985

Assessing optimal: inequalities in codon optimization algorithms.

Ranaghan MJ, Li JJ, Laprise DM, Garvie CW. Assessing optimal: inequalities in codon optimization algorithms. BMC Biol. 2021;19(1):36. doi:10.1186/s12915-021-00968-8

Clinically relevant mutations in core metabolic genes confer antibiotic resistance.

Lopatkin AJ, Bening SC, Manson AL, et al. Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science. 2021;371(6531). doi:10.1126/science.aba0862

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors.

Richters A, Doyle SK, Freeman DB, et al. Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors. Cell Chem Biol. 2021;28(2):134-147.e14. doi:10.1016/j.chembiol.2020.10.001