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Publications

Mapping transcriptomic vector fields of single cells.

Qiu X, Zhang Y, Martin-Rufino JD, et al. Mapping transcriptomic vector fields of single cells. Cell. 2022. doi:10.1016/j.cell.2021.12.045

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.

Khadka P, Reitman ZJ, Lu S, et al. PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. Nat Commun. 2022;13(1):604. doi:10.1038/s41467-022-28198-8

Somatic and germline genomic alterations in very young women with breast cancer.

Waks AG, Kim D, Jain E, et al. Somatic and germline genomic alterations in very young women with breast cancer. Clin Cancer Res. 2022. doi:10.1158/1078-0432.CCR-21-2572

Thalamic subnetworks as units of function.

Roy DS, Zhang Y, Halassa MM, Feng G. Thalamic subnetworks as units of function. Nat Neurosci. 2022. doi:10.1038/s41593-021-00996-1

Towards a Better Understanding of Antibody-Drug Conjugates in Urothelial Carcinoma.

Labaki C, Bakouny Z, Sonpavde G, Choueiri TK, Van Allen EM. Towards a Better Understanding of Antibody-Drug Conjugates in Urothelial Carcinoma. Eur Urol Oncol. 2022. doi:10.1016/j.euo.2022.01.004

Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 individuals Across 13 Cohorts.

DiCorpo D, LeClair J, Cole JB, et al. Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 individuals Across 13 Cohorts. Diabetes Care. 2022. doi:10.2337/dc21-1395

Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.

Stover EH, Oh C, Keskula P, et al. Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples. Prostate. 2022. doi:10.1002/pros.24305

Leveraging gene co-regulation to identify gene sets enriched for disease heritability.

Siewert-Rocks KM, Kim SS, Yao DW, Shi H, Price AL. Leveraging gene co-regulation to identify gene sets enriched for disease heritability. Am J Hum Genet. 2022. doi:10.1016/j.ajhg.2022.01.005

Sparse dictionary learning recovers pleiotropy from human cell fitness screens.

Pan J, Kwon JJ, Talamas JA, et al. Sparse dictionary learning recovers pleiotropy from human cell fitness screens. Cell Syst. 2022. doi:10.1016/j.cels.2021.12.005

The new era of quantitative cell imaging-challenges and opportunities.

Bagheri N, Carpenter AE, Lundberg E, Plant AL, Horwitz R. The new era of quantitative cell imaging-challenges and opportunities. Mol Cell. 2022;82(2):241-247. doi:10.1016/j.molcel.2021.12.024