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Publications

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

Bowling S, Sritharan D, Osorio FG, et al. An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells. Cell. 2020. doi:10.1016/j.cell.2020.04.048

The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor positive metastatic breast cancer.

Wander SA, Cohen O, Gong X, et al. The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor positive metastatic breast cancer. Cancer Discov. 2020. doi:10.1158/2159-8290.CD-19-1390

Role of Sphingolipid Metabolism in Neurodegeneration.

Alaamery M, Albesher N, Aljawini N, et al. Role of Sphingolipid Metabolism in Neurodegeneration. J Neurochem. 2020. doi:10.1111/jnc.15044

Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies.

Williams SE, Mealer RG, Scolnick EM, Smoller JW, Cummings RD. Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies. Mol Psychiatry. 2020. doi:10.1038/s41380-020-0761-1

Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention.

Figarska SM, Rigdon J, Ganna A, et al. Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention. Sci Rep. 2020;10(1):7913. doi:10.1038/s41598-020-64636-7

Using Chemical Epigenetics to Target Cancer.

Wimalasena VK, Wang T, Sigua LH, Durbin AD, Qi J. Using Chemical Epigenetics to Target Cancer. Mol Cell. 2020. doi:10.1016/j.molcel.2020.04.023

Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data.

Shi H, Burch KS, Johnson R, et al. Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data. Am J Hum Genet. 2020. doi:10.1016/j.ajhg.2020.04.012

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris.

Rybak JM, Muñoz JF, Barker KS, et al. Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris. mBio. 2020;11(3). doi:10.1128/mBio.00365-20

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.

Byrne EM, Zhu Z, Qi T, et al. Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Mol Psychiatry. 2020. doi:10.1038/s41380-020-0705-9

Genetics of diabetes mellitus and diabetes complications.

Cole JB, Florez JC. Genetics of diabetes mellitus and diabetes complications. Nat Rev Nephrol. 2020. doi:10.1038/s41581-020-0278-5