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Publications

Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.

Marchesini M, Gherli A, Montanaro A, et al. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol. 2020. doi:10.1016/j.chembiol.2020.04.002

Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence.

Lett TA, Vogel BO, Ripke S, et al. Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence. Cereb Cortex. 2020;30(4):2707-2718. doi:10.1093/cercor/bhz270

Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors.

Zhang Z, Mäkinen N, Kasai Y, et al. Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors. Genes Chromosomes Cancer. 2020. doi:10.1002/gcc.22850

Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.

Ernst CM, Braxton JR, Rodriguez-Osorio CA, et al. Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nat Med. 2020. doi:10.1038/s41591-020-0825-4

Design and analysis of CRISPR-Cas experiments.

Hanna RE, Doench JG. Design and analysis of CRISPR-Cas experiments. Nat Biotechnol. 2020. doi:10.1038/s41587-020-0490-7

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.

Kaminski MM, Alcantar MA, Lape IT, et al. A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection. Nat Biomed Eng. 2020. doi:10.1038/s41551-020-0546-5

Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.

Ding J, Adiconis X, Simmons SK, et al. Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. Nat Biotechnol. 2020. doi:10.1038/s41587-020-0465-8

Discovery of a selective inhibitor of doublecortin like kinase 1.

Ferguson FM, Nabet B, Raghavan S, et al. Discovery of a selective inhibitor of doublecortin like kinase 1. Nat Chem Biol. 2020. doi:10.1038/s41589-020-0506-0

MYC Controls the Epstein-Barr Virus Lytic Switch.

Guo R, Jiang C, Zhang Y, et al. MYC Controls the Epstein-Barr Virus Lytic Switch. Mol Cell. 2020. doi:10.1016/j.molcel.2020.03.025

Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism.

Jain IH, Calvo SE, Markhard AL, et al. Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism. Cell. 2020. doi:10.1016/j.cell.2020.03.029