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Publications

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.

Anastas JN, Zee BM, Kalin JH, et al. Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. 2019;36(5):528-544.e10. doi:10.1016/j.ccell.2019.09.005

Combinatorial Targeting of Distributed Forebrain Networks Reverses Noise Hypersensitivity in a Model of Autism Spectrum Disorder.

Nakajima M, Schmitt I, Feng G, Halassa MM. Combinatorial Targeting of Distributed Forebrain Networks Reverses Noise Hypersensitivity in a Model of Autism Spectrum Disorder. Neuron. 2019;104(3):488-500.e11. doi:10.1016/j.neuron.2019.09.040

LDAF1 and Seipin Form a Lipid Droplet Assembly Complex.

Chung J, Wu X, Lambert TJ, Lai ZW, Walther TC, Farese RV. LDAF1 and Seipin Form a Lipid Droplet Assembly Complex. Dev Cell. 2019. doi:10.1016/j.devcel.2019.10.006

Identification of Candida auris by Use of the Updated Vitek 2 Yeast Identification System, Version 8.01: a Multilaboratory Evaluation Study.

Ambaraghassi G, Dufresne PJ, Dufresne SF, et al. Identification of Candida auris by Use of the Updated Vitek 2 Yeast Identification System, Version 8.01: a Multilaboratory Evaluation Study. J Clin Microbiol. 2019;57(11). doi:10.1128/JCM.00884-19

Chinese scientists and US leadership in the life sciences.

Holtzman SH, Cohen R, Levin JM, Maraganore J, Signatories to the Statement. Chinese scientists and US leadership in the life sciences. Nat Biotechnol. 2019;37(11):1261-1263. doi:10.1038/s41587-019-0285-x

Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.

Flavahan WA, Drier Y, Johnstone SE, et al. Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs. Nature. 2019;575(7781):229-233. doi:10.1038/s41586-019-1668-3

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.

Klarin D, Busenkell E, Judy R, et al. Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet. 2019;51(11):1574-1579. doi:10.1038/s41588-019-0519-3

Scaling computational genomics to millions of individuals with GPUs.

Taylor-Weiner A, Aguet F, Haradhvala NJ, et al. Scaling computational genomics to millions of individuals with GPUs. Genome Biol. 2019;20(1):228. doi:10.1186/s13059-019-1836-7

Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.

Stover EH, Baco MB, Cohen O, et al. Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer. Mol Cancer Res. 2019;17(11):2281-2293. doi:10.1158/1541-7786.MCR-18-1243

Metabolome-Wide Association Study of the Relationship Between Habitual Physical Activity and Plasma Metabolite Levels.

Ding M, Zeleznik OA, Guasch-Ferre M, et al. Metabolome-Wide Association Study of the Relationship Between Habitual Physical Activity and Plasma Metabolite Levels. American journal of epidemiology. 2019;188(11):1932-1943. doi:10.1093/aje/kwz171