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Publications

Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans.

Muñoz JF, Delorey T, Ford CB, et al. Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans. Nat Commun. 2019;10(1):1607. doi:10.1038/s41467-019-09599-8

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.

Zou Y, Palte MJ, Deik AA, et al. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nat Commun. 2019;10(1):1617. doi:10.1038/s41467-019-09277-9

The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study.

Azarbarzin A, Sands SA, Stone KL, et al. The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study. Eur Heart J. 2019;40(14):1149-1157. doi:10.1093/eurheartj/ehy624

IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.

Amariuta T, Luo Y, Gazal S, et al. IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors. Am J Hum Genet. 2019. doi:10.1016/j.ajhg.2019.03.012

Rare Protein-truncating Variants in APOB, Lower LDL-C, and Protection Against Coronary Heart Disease.

Peloso GM, Nomura A, Khera AV, et al. Rare Protein-truncating Variants in APOB, Lower LDL-C, and Protection Against Coronary Heart Disease. Circ Genom Precis Med. 2019. doi:10.1161/CIRCGEN.118.002376

Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD Recycling.

Kim W, Deik A, Gonzalez C, et al. Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD Recycling. Cell Metab. 2019;29(4):856-870.e7. doi:10.1016/j.cmet.2018.12.023

Extending the clinical and mutational spectrum of -related myopathies in a non-Hutterite population.

Johnson K, De Ridder W, Topf A, et al. Extending the clinical and mutational spectrum of -related myopathies in a non-Hutterite population. J Neurol Neurosurg Psychiatry. 2019;90(4):490-493. doi:10.1136/jnnp-2018-318288

Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus.

Vanhala V, Junkkari A, Korhonen VE, et al. Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus. Neurosurgery. 2019;84(4):883-889. doi:10.1093/neuros/nyy147

WRN helicase is a synthetic lethal target in microsatellite unstable cancers.

Chan EM, Shibue T, McFarland JM, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568(7753):551-556. doi:10.1038/s41586-019-1102-x

Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke.

Berntsson J, Smith G, Johnson LSB, et al. Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke. Heart. 2019;105(7):553-558. doi:10.1136/heartjnl-2018-313684