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Publications

Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies.

Razquin C, Ruiz-Canela M, Clish CB, et al. Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies. Cardiovascular diabetology. 2019;18(1):151. doi:10.1186/s12933-019-0958-2

Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis.

Liu PH, Burke KE, Ananthakrishnan AN, et al. Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis. Clin Gastroenterol Hepatol. 2019;17(12):2523-2532.e1. doi:10.1016/j.cgh.2018.11.057

Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies.

Wu Y, Hormozdiari F, Joo JWJ, Eskin E. Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. J Comput Biol. 2019;26(11):1203-1213. doi:10.1089/cmb.2018.0139

Erratum for the Research Article: "A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough"

Erratum for the Research Article: "A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough". Sci Transl Med. 2019;11(516). doi:10.1126/scitranslmed.aaz9925

Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.

Brumbaugh J, Kim IS, Ji F, et al. Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nat Cell Biol. 2019. doi:10.1038/s41556-019-0403-5

Structural basis for the docking of mTORC1 on the lysosomal surface.

Rogala KB, Gu X, Kedir JF, et al. Structural basis for the docking of mTORC1 on the lysosomal surface. Science. 2019;366(6464):468-475. doi:10.1126/science.aay0166

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration.

Menon M, Mohammadi S, Davila-Velderrain J, et al. Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration. Nat Commun. 2019;10(1):4902. doi:10.1038/s41467-019-12780-8

A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough.

Ahmad R, Xie L, Pyle M, et al. A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough. Sci Transl Med. 2019;11(515). doi:10.1126/scitranslmed.aaw8287

Search-and-replace genome editing without double-strand breaks or donor DNA.

Anzalone AV, Randolph PB, Davis JR, et al. Search-and-replace genome editing without double-strand breaks or donor DNA. Nature. 2019. doi:10.1038/s41586-019-1711-4

Absolute Free Energy of Binding Calculations for Macrophage Migration Inhibitory Factor in Complex with a Druglike Inhibitor.

Qian Y, de Vaca IC, Vilseck JZ, Cole DJ, Tirado-Rives J, Jorgensen WL. Absolute Free Energy of Binding Calculations for Macrophage Migration Inhibitory Factor in Complex with a Druglike Inhibitor. J Phys Chem B. 2019;123(41):8675-8685. doi:10.1021/acs.jpcb.9b07588