St Laurent JD, Xu GD, Ying AW, et al. Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas. Nature genetics. 2025. doi:10.1038/s41588-025-02333-9
Epigenomics
Waterbury AL, Kwok HS, Lee C, et al. An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular cell. 2024. doi:10.1016/j.molcel.2024.05.017
Labade A, Chiang Z, Comenho C, et al. Expansion genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.24.614614
Kim KL, Rahme GJ, Goel VY, Farran CAE, Hansen AS, Bernstein BE. Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation. Molecular cell. 2024. doi:10.1016/j.molcel.2024.02.007
Lue NZ, Garcia EM, Ngan K, Lee C, Doench JG, Liau BB. Base editor scanning charts the DNMT3A activity landscape. Nature chemical biology. 2023;19(2):176-186. doi:10.1038/s41589-022-01167-4
Kwok HS, Freedy AM, Siegenfeld AP, et al. Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma. Nature chemical biology. 2023. doi:10.1038/s41589-023-01299-1
Rozowsky J, Gao J, Borsari B, et al. The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models. Cell. 2023;186(7):1493-1511.e40. doi:10.1016/j.cell.2023.02.018
Najm FJ, DeWeirdt P, Moore MM, et al. Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications. 2023;14(1):448. doi:10.1038/s41467-023-36150-7
Mangiameli SM, Chen H, Earl AS, et al. Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution. Nature methods. 2023;20(5):686-694. doi:10.1038/s41592-023-01845-8
Martin-Rufino JD, Castano N, Pang M, et al. Massively parallel base editing to map variant effects in human hematopoiesis. Cell. 2023. doi:10.1016/j.cell.2023.03.035