Chen Z, Javed N, Moore M, et al. Integrative dissection of gene regulatory elements at base resolution. Cell genomics. 2023;3(6):100318. doi:10.1016/j.xgen.2023.100318
Epigenomics
Lue NZ, Garcia EM, Ngan K, Lee C, Doench JG, Liau BB. Base editor scanning charts the DNMT3A activity landscape. Nature chemical biology. 2023;19(2):176-186. doi:10.1038/s41589-022-01167-4
Goel VY, Huseyin MK, Hansen AS. Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. Nature genetics. 2023. doi:10.1038/s41588-023-01391-1
Kwok HS, Freedy AM, Siegenfeld AP, et al. Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma. Nature chemical biology. 2023. doi:10.1038/s41589-023-01299-1
Joung J, Ma S, Tay T, et al. A transcription factor atlas of directed differentiation. Cell. 2023;186(1):209-229.e26. doi:10.1016/j.cell.2022.11.026
Cancellieri S, Zeng J, Lin L, et al. Human genetic diversity alters off-target outcomes of therapeutic gene editing. Nature genetics. 2023;55(1):34-43. doi:10.1038/s41588-022-01257-y
Rozowsky J, Gao J, Borsari B, et al. The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models. Cell. 2023;186(7):1493-1511.e40. doi:10.1016/j.cell.2023.02.018
Najm FJ, DeWeirdt P, Moore MM, et al. Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature communications. 2023;14(1):448. doi:10.1038/s41467-023-36150-7
Martin BJE, Ablondi EF, Goglia C, Mimoso CA, Espinel-Cabrera PR, Adelman K. Global identification of SWI/SNF targets reveals compensation by EP400. Cell. 2023;186(24):5290-5307.e26. doi:10.1016/j.cell.2023.10.006
Battaglia S, Dong K, Wu J, et al. Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. Nat Genet. 2022;54(10):1504-1513. doi:10.1038/s41588-022-01188-8