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Epigenomics
Waterbury AL, Kwok HS, Lee C, et al. An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular cell. 2024. doi:10.1016/j.molcel.2024.05.017
Labade A, Chiang Z, Comenho C, et al. Expansion genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.24.614614
Goel VY, Huseyin MK, Hansen AS. Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. Nature genetics. 2023. doi:10.1038/s41588-023-01391-1
Joung J, Ma S, Tay T, et al. A transcription factor atlas of directed differentiation. Cell. 2023;186(1):209-229.e26. doi:10.1016/j.cell.2022.11.026
Martin-Rufino JD, Castano N, Pang M, et al. Massively parallel base editing to map variant effects in human hematopoiesis. Cell. 2023. doi:10.1016/j.cell.2023.03.035
Cancellieri S, Zeng J, Lin L, et al. Human genetic diversity alters off-target outcomes of therapeutic gene editing. Nature genetics. 2023;55(1):34-43. doi:10.1038/s41588-022-01257-y
Kwok HS, Freedy AM, Siegenfeld AP, et al. Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma. Nature chemical biology. 2023. doi:10.1038/s41589-023-01299-1
Rahme GJ, Javed NM, Puorro KL, et al. Modeling epigenetic lesions that cause gliomas. Cell. 2023. doi:10.1016/j.cell.2023.06.022
Chen Z, Javed N, Moore M, et al. Integrative dissection of gene regulatory elements at base resolution. Cell genomics. 2023;3(6):100318. doi:10.1016/j.xgen.2023.100318