Choi J, Huebner AJ, Clement K, et al. Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature. 2017;548(7666):219-223. doi:10.1038/nature23274
Epigenomics
Gupta RM, Hadaya J, Trehan A, et al. A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. Cell. 2017;170(3):522-533.e15. doi:10.1016/j.cell.2017.06.049
Choi J, Clement K, Huebner AJ, et al. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell. 2017;20(5):706-719.e7. doi:10.1016/j.stem.2017.03.002
Warren CR, O’Sullivan JF, Friesen M, et al. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell. 2017;20(4):547-557.e7. doi:10.1016/j.stem.2017.01.010
Yu VWC, Yusuf RZ, Oki T, et al. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 2016;167(5):1310-1322.e17. doi:10.1016/j.cell.2016.10.045
Wang X, Tucker NR, Rizki G, et al. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016;5. doi:10.7554/eLife.10557
Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE. Single-molecule decoding of combinatorially modified nucleosomes. Science. 2016;352(6286):717-21. doi:10.1126/science.aad7701
van Galen P, Viny AD, Ram O, et al. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell. 2016;61(1):170-80. doi:10.1016/j.molcel.2015.11.003
Ziller MJ, Stamenova EK, Gu H, Gnirke A, Meissner A. Targeted bisulfite sequencing of the dynamic DNA methylome. Epigenetics Chromatin. 2016;9:55. doi:10.1186/s13072-016-0105-1
Tsai S, Topkar V V, Joung K, Aryee M. Open-source guideseq software for analysis of GUIDE-seq data. Nature biotechnology. 2016;34(5):483. doi:10.1038/nbt.3534