ӳ��ý

Epigenomics

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.

van Galen P, Viny AD, Ram O, et al. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell. 2016;61(1):170-80. doi:10.1016/j.molcel.2015.11.003

Open-source guideseq software for analysis of GUIDE-seq data.

Tsai S, Topkar V V, Joung K, Aryee M. Open-source guideseq software for analysis of GUIDE-seq data. Nature biotechnology. 2016;34(5):483. doi:10.1038/nbt.3534

Targeted bisulfite sequencing of the dynamic DNA methylome.

Ziller MJ, Stamenova EK, Gu H, Gnirke A, Meissner A. Targeted bisulfite sequencing of the dynamic DNA methylome. Epigenetics Chromatin. 2016;9:55. doi:10.1186/s13072-016-0105-1

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.

Rotem A, Ram O, Shoresh N, et al. Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state. Nat Biotechnol. 2015;33(11):1165-72. doi:10.1038/nbt.3383

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.

Claussnitzer M, Dankel SN, Kim KH, et al. FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. N Engl J Med. 2015;373(10):895-907. doi:10.1056/NEJMoa1502214

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency.

Cacchiarelli D, Trapnell C, Ziller MJ, et al. Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency. Cell. 2015;162(2):412-24. doi:10.1016/j.cell.2015.06.016

Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing.

Ziller MJ, Hansen KD, Meissner A, Aryee MJ. Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing. Nat Methods. 2015;12(3):230-2, 1 p following 232. doi:10.1038/nmeth.3152

Transcription factor binding dynamics during human ES cell differentiation.

Tsankov AM, Gu H, Akopian V, et al. Transcription factor binding dynamics during human ES cell differentiation. Nature. 2015;518(7539):344-9. doi:10.1038/nature14233

Dissecting neural differentiation regulatory networks through epigenetic footprinting.

Ziller MJ, Edri R, Yaffe Y, et al. Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 2015;518(7539):355-9. doi:10.1038/nature13990

Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Farh KKH, Marson A, Zhu J, et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature. 2015;518(7539):337-43. doi:10.1038/nature13835