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Epigenomics
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Johnstone S, Gladyshev V, Aryee M, Bernstein B. Epigenetic clocks, aging, and cancer. Science (New York, N.Y.). 2022;378(6626):1276-1277. doi:10.1126/science.abn4009
Miller T, Lareau C, Verga J, et al. Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations. Nature biotechnology. 2022;40(7):1030-1034. doi:10.1038/s41587-022-01210-8
Vlaming H, Mimoso C, Field A, Martin B, Adelman K. Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential. Nature structural & molecular biology. 2022;29(6):613-620. doi:10.1038/s41594-022-00785-9
de Goede O. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. 2021;184(10):2633-2648.e19. doi:10.1016/j.cell.2021.03.050
Tognon M, Bonnici V, Garrison E, Giugno R, Pinello L. GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs. PLoS computational biology. 2021;17(9):e1009444. doi:10.1371/journal.pcbi.1009444
Ma S. Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin. Cell. 2020;183(4):1103-1116.e20. doi:10.1016/j.cell.2020.09.056
Kim-Hellmuth S. Cell type-specific genetic regulation of gene expression across human tissues. Science (New York, N.Y.). 2020;369(6509). doi:10.1126/science.aaz8528
Vinyard ME, Su C, Siegenfeld AP, et al. CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nat Chem Biol. 2019;15(5):529-539. doi:10.1038/s41589-019-0263-0