ӳ��ý

Epigenomics

Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling.

Boyle P, Clement K, Gu H, et al. Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling. Genome Biol. 2012;13(10):R92. doi:10.1186/gb-2012-13-10-r92

An integrated encyclopedia of DNA elements in the human genome.

ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57-74. doi:10.1038/nature11247

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.

Landt S, Marinov G, Kundaje A, et al. ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome research. 2012;22(9):1813-31. doi:10.1101/gr.136184.111

Points of view: Data exploration.

Shoresh N, Wong B. Points of view: Data exploration. Nature methods. 2012;9(1):5.

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk.

Brinkman A, Gu H, Bartels S, et al. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome research. 2012;22(6):1128-38. doi:10.1101/gr.133728.111

Mapping and analysis of chromatin state dynamics in nine human cell types.

Ernst J, Kheradpour P, Mikkelsen T, et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature. 2011;473(7345):43-9. doi:10.1038/nature09906

Comparative epigenomic analysis of murine and human adipogenesis.

Mikkelsen TS, Xu Z, Zhang X, et al. Comparative epigenomic analysis of murine and human adipogenesis. Cell. 2010;143(1):156-69. doi:10.1016/j.cell.2010.09.006

Genome-scale DNA methylation maps of pluripotent and differentiated cells.

Meissner A, Mikkelsen TS, Gu H, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 2008;454(7205):766-70. doi:10.1038/nature07107