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Imaging Platform

A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax.

March S, Ng S, Velmurugan S, et al. A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe. 2013;14(1):104-15. doi:10.1016/j.chom.2013.06.005

Multiplex cytological profiling assay to measure diverse cellular states.

Gustafsdottir SM, Ljosa V, Sokolnicki KL, et al. Multiplex cytological profiling assay to measure diverse cellular states. PLoS One. 2013;8(12):e80999. doi:10.1371/journal.pone.0080999

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.

Wen Q, Goldenson B, Silver SJ, et al. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 2012;150(3):575-89. doi:10.1016/j.cell.2012.06.032

Annotated high-throughput microscopy image sets for validation.

Ljosa V, Sokolnicki KL, Carpenter AE. Annotated high-throughput microscopy image sets for validation. Nat Methods. 2012;9(7):637. doi:10.1038/nmeth.2083

A call for bioimaging software usability.

Carpenter AE, Kamentsky L, Eliceiri KW. A call for bioimaging software usability. Nat Methods. 2012;9(7):666-70. doi:10.1038/nmeth.2073

An image analysis toolbox for high-throughput C. elegans assays.

Wählby C, Kamentsky L, Liu ZH, et al. An image analysis toolbox for high-throughput C. elegans assays. Nat Methods. 2012;9(7):714-6. doi:10.1038/nmeth.1984

Workflow and metrics for image quality control in large-scale high-content screens.

Bray MA, Fraser AN, Hasaka TP, Carpenter AE. Workflow and metrics for image quality control in large-scale high-content screens. J Biomol Screen. 2012;17(2):266-74. doi:10.1177/1087057111420292

A chemical screen probing the relationship between mitochondrial content and cell size.

Kitami T, Logan DJ, Negri J, et al. A chemical screen probing the relationship between mitochondrial content and cell size. PLoS One. 2012;7(3):e33755. doi:10.1371/journal.pone.0033755

Visualization of parameter space for image analysis.

Pretorius J, Bray MAP, Carpenter AE, Ruddle RA. Visualization of parameter space for image analysis. IEEE Trans Vis Comput Graph. 2011;17(12):2402-11. doi:10.1109/TVCG.2011.253

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice.

Elkabets M, Gifford AM, Scheel C, et al. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest. 2011;121(2):784-99. doi:10.1172/JCI43757