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Imaging Platform

Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging.

Tomov ML, O’Neil A, Abbasi HS, et al. Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging. Commun Biol. 2021;4(1):786. doi:10.1038/s42003-021-02276-x

Which image-based phenotypes are most promising for using AI to understand cellular functions and why?

Lundberg E, Funke J, Uhlmann V, et al. Which image-based phenotypes are most promising for using AI to understand cellular functions and why?. Cell Syst. 2021;12(5):384-387. doi:10.1016/j.cels.2021.04.012

ImageJ and CellProfiler: Complements in Open-Source Bioimage Analysis.

Dobson ETA, Cimini B, Klemm AH, Wählby C, Carpenter AE, Eliceiri KW. ImageJ and CellProfiler: Complements in Open-Source Bioimage Analysis. Curr Protoc. 2021;1(5):e89. doi:10.1002/cpz1.89

Developing open-source software for bioimage analysis: opportunities and challenges.

Levet F, Carpenter AE, Eliceiri KW, Kreshuk A, Bankhead P, Haase R. Developing open-source software for bioimage analysis: opportunities and challenges. F1000Res. 2021;10:302. doi:10.12688/f1000research.52531.1

TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.

Carey KL, Paulus GLC, Wang L, et al. TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41. Cell Rep. 2020;33(6):108371. doi:10.1016/j.celrep.2020.108371

Diagnostic Potential of Imaging Flow Cytometry.

Doan M, Vorobjev I, Rees P, et al. Diagnostic Potential of Imaging Flow Cytometry. Trends Biotechnol. 2018;36(7):649-652. doi:10.1016/j.tibtech.2017.12.008

CellProfiler 3.0: Next-generation image processing for biology.

McQuin C, Goodman A, Chernyshev V, et al. CellProfiler 3.0: Next-generation image processing for biology. PLoS Biol. 2018;16(7):e2005970. doi:10.1371/journal.pbio.2005970

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, et al. Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery. Cell Chem Biol. 2018;25(5):611-618.e3. doi:10.1016/j.chembiol.2018.01.015

Opportunities and obstacles for deep learning in biology and medicine.

Ching T, Himmelstein DS, Beaulieu-Jones BK, et al. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018;15(141). doi:10.1098/rsif.2017.0387

Designed Surface Topographies Control ICAM-1 Expression in Tonsil-Derived Human Stromal Cells.

Vasilevich AS, Mourcin F, Mentink A, et al. Designed Surface Topographies Control ICAM-1 Expression in Tonsil-Derived Human Stromal Cells. Front Bioeng Biotechnol. 2018;6:87. doi:10.3389/fbioe.2018.00087