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Metabolomics Platform

Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus.

Tobias DK, Hamaya R, Clish CB, et al. Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus. Diabetes/metabolism research and reviews. 2024;40(1):e3763. doi:10.1002/dmrr.3763

Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Wulczyn KE, Shafi T, Anderson A, et al. Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2024. doi:10.1053/j.ajkd.2023.11.013

Genetic factors affecting storage and utilization of lipids during dormancy in .

Sturm A, Sun P, Avila-Pacheco J, et al. Genetic factors affecting storage and utilization of lipids during dormancy in . mBio. 2024:e0320823. doi:10.1128/mbio.03208-23

Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.

Schirmer M, Stražar M, Avila-Pacheco J, et al. Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course. Cell host & microbe. 2024. doi:10.1016/j.chom.2023.12.013

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.

Singh C, Jin B, Shrestha N, et al. ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell metabolism. 2024;36(1):144-158.e7. doi:10.1016/j.cmet.2023.11.010

Changes in Bile Acid Subtypes and Improvements in Lipid Metabolism and Atherosclerotic Cardiovascular Disease Risk: The POUNDS Lost trial.

Heianza Y, Xue Q, Rood J, et al. Changes in Bile Acid Subtypes and Improvements in Lipid Metabolism and Atherosclerotic Cardiovascular Disease Risk: The POUNDS Lost trial. The American journal of clinical nutrition. 2024. doi:10.1016/j.ajcnut.2024.02.019

Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies.

Tessier AJ, Wang F, Liang L, et al. Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies. Med (New York, N.Y.). 2024. doi:10.1016/j.medj.2024.01.010

Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia.

Mondal AK, Brock DC, Rowan S, et al. Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia. iScience. 2024;27(2):108979. doi:10.1016/j.isci.2024.108979

The menopause-related gut microbiome: associations with metabolomics, inflammatory protein markers, and cardiometabolic health in women with HIV.

Wang Y, Sharma A, Weber KM, et al. The menopause-related gut microbiome: associations with metabolomics, inflammatory protein markers, and cardiometabolic health in women with HIV. Menopause (New York, N.Y.). 2024;31(1):52-64. doi:10.1097/GME.0000000000002287

Implications of metabolism on multi-systems healthy aging across the lifespan.

Yao S, Colangelo LA, Perry AS, et al. Implications of metabolism on multi-systems healthy aging across the lifespan. Aging cell. 2024:e14090. doi:10.1111/acel.14090