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Metabolomics Platform

Plasma Proteomics of Exercise Blood Pressure and Incident Hypertension.

Rao P, Keyes MJ, Mi MY, et al. Plasma Proteomics of Exercise Blood Pressure and Incident Hypertension. JAMA cardiology. 2024. doi:10.1001/jamacardio.2024.1397

Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies.

Tessier AJ, Wang F, Liang L, et al. Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies. Med (New York, N.Y.). 2024. doi:10.1016/j.medj.2024.01.010

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell W, Goeminne LJE, Tyshkovskiy A, et al. Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife. 2024;12. doi:10.7554/eLife.90579

Changes in Bile Acid Subtypes and Improvements in Lipid Metabolism and Atherosclerotic Cardiovascular Disease Risk: The POUNDS Lost trial.

Heianza Y, Xue Q, Rood J, et al. Changes in Bile Acid Subtypes and Improvements in Lipid Metabolism and Atherosclerotic Cardiovascular Disease Risk: The POUNDS Lost trial. The American journal of clinical nutrition. 2024. doi:10.1016/j.ajcnut.2024.02.019

Lac-Phe mediates the effects of metformin on food intake and body weight.

Xiao S, Li VL, Lyu X, et al. Lac-Phe mediates the effects of metformin on food intake and body weight. Nature metabolism. 2024. doi:10.1038/s42255-024-00999-9

Metabolic liability for weight gain in early adulthood.

Murthy VL, Mosley JD, Perry AS, et al. Metabolic liability for weight gain in early adulthood. Cell reports. Medicine. 2024:101548. doi:10.1016/j.xcrm.2024.101548

Tryptophan-kynurenine metabolic pathway and daytime dysfunction in women with HIV.

Shorer EF, Rubin LH, French AL, et al. Tryptophan-kynurenine metabolic pathway and daytime dysfunction in women with HIV. Journal of neurovirology. 2024. doi:10.1007/s13365-024-01195-x

Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus.

Tobias DK, Hamaya R, Clish CB, et al. Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus. Diabetes/metabolism research and reviews. 2024;40(1):e3763. doi:10.1002/dmrr.3763

Implications of metabolism on multi-systems healthy aging across the lifespan.

Yao S, Colangelo LA, Perry AS, et al. Implications of metabolism on multi-systems healthy aging across the lifespan. Aging cell. 2024:e14090. doi:10.1111/acel.14090

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food.

Iman MN, Haslam DE, Liang L, et al. Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food. Food chemistry. 2024;446:138744. doi:10.1016/j.foodchem.2024.138744