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Metabolomics Platform

Genetic factors affecting storage and utilization of lipids during dormancy in .

Sturm A, Sun P, Avila-Pacheco J, et al. Genetic factors affecting storage and utilization of lipids during dormancy in . mBio. 2024:e0320823. doi:10.1128/mbio.03208-23

Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults.

Haslam DE, Liang L, Guo K, et al. Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults. Diabetologia. 2024. doi:10.1007/s00125-024-06169-6

Lac-Phe mediates the effects of metformin on food intake and body weight.

Xiao S, Li VL, Lyu X, et al. Lac-Phe mediates the effects of metformin on food intake and body weight. Nature metabolism. 2024. doi:10.1038/s42255-024-00999-9

Longitudinal Plasma Metabolome Patterns and Relation to Kidney Function and Proteinuria in Pediatric CKD.

Lee AM, Xu Y, Hu J, et al. Longitudinal Plasma Metabolome Patterns and Relation to Kidney Function and Proteinuria in Pediatric CKD. Clinical journal of the American Society of Nephrology : CJASN. 2024. doi:10.2215/CJN.0000000000000463

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.

Singh C, Jin B, Shrestha N, et al. ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell metabolism. 2024;36(1):144-158.e7. doi:10.1016/j.cmet.2023.11.010

Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue.

Many GM, Sanford JA, Sagendorf TJ, et al. Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Nature metabolism. 2024;6(5):963-979. doi:10.1038/s42255-023-00959-9

Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Wulczyn KE, Shafi T, Anderson A, et al. Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2024. doi:10.1053/j.ajkd.2023.11.013

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Human Studies Design and Protocol.

Group MR, Jakicic JM, Kohrt WM, et al. Molecular Transducers of Physical Activity Consortium (MoTrPAC): Human Studies Design and Protocol. Journal of applied physiology (Bethesda, Md. : 1985). 2024. doi:10.1152/japplphysiol.00102.2024

Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.

Schirmer M, Stražar M, Avila-Pacheco J, et al. Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course. Cell host & microbe. 2024. doi:10.1016/j.chom.2023.12.013

Metabolic liability for weight gain in early adulthood.

Murthy VL, Mosley JD, Perry AS, et al. Metabolic liability for weight gain in early adulthood. Cell reports. Medicine. 2024:101548. doi:10.1016/j.xcrm.2024.101548