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Metabolomics Platform

Integrated annotation prioritizes metabolites with bioactivity in inflammatory bowel disease.

Bhosle A, Bae S, Zhang Y, et al. Integrated annotation prioritizes metabolites with bioactivity in inflammatory bowel disease. Molecular systems biology. 2024. doi:10.1038/s44320-024-00027-8

Genetic factors affecting storage and utilization of lipids during dormancy in .

Sturm A, Sun P, Avila-Pacheco J, et al. Genetic factors affecting storage and utilization of lipids during dormancy in . mBio. 2024:e0320823. doi:10.1128/mbio.03208-23

Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia.

Mondal AK, Brock DC, Rowan S, et al. Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia. iScience. 2024;27(2):108979. doi:10.1016/j.isci.2024.108979

The menopause-related gut microbiome: associations with metabolomics, inflammatory protein markers, and cardiometabolic health in women with HIV.

Wang Y, Sharma A, Weber KM, et al. The menopause-related gut microbiome: associations with metabolomics, inflammatory protein markers, and cardiometabolic health in women with HIV. Menopause (New York, N.Y.). 2024;31(1):52-64. doi:10.1097/GME.0000000000002287

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell W, Goeminne LJE, Tyshkovskiy A, et al. Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife. 2024;12. doi:10.7554/eLife.90579

Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial.

García-Gavilán JF, Atzeni A, Babio N, et al. Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial. The American journal of clinical nutrition. 2024. doi:10.1016/j.ajcnut.2024.02.021

Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus.

Tobias DK, Hamaya R, Clish CB, et al. Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus. Diabetes/metabolism research and reviews. 2024;40(1):e3763. doi:10.1002/dmrr.3763

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.

Singh C, Jin B, Shrestha N, et al. ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell metabolism. 2024;36(1):144-158.e7. doi:10.1016/j.cmet.2023.11.010

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food.

Iman MN, Haslam DE, Liang L, et al. Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food. Food chemistry. 2024;446:138744. doi:10.1016/j.foodchem.2024.138744

Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities.

Li Y, Hong X, Chandran A, et al. Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024. doi:10.1016/j.anai.2024.03.001