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Metabolomics Platform

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis.

Gohil VM, Sheth SA, Nilsson R, et al. Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nat Biotechnol. 2010;28(3):249-55. doi:10.1038/nbt.1606

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells.

Shaham O, Slate NG, Goldberger O, et al. A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells. Proc Natl Acad Sci U S A. 2010;107(4):1571-5. doi:10.1073/pnas.0906039107

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.

Zhong L, D’Urso A, Toiber D, et al. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell. 2010;140(2):280-93. doi:10.1016/j.cell.2009.12.041

New nucleotide sequence data on the EMBL File Server.

New nucleotide sequence data on the EMBL File Server. Nucleic acids research. 1991;19(2):413-21.

Tension pneumocephalus following insertion of ventriculoatrial shunt after severe head trauma. Case report.

Muizelaar JP, Walder HA. Tension pneumocephalus following insertion of ventriculoatrial shunt after severe head trauma. Case report. Clinical neurology and neurosurgery. 1977;80(1):57-61.