Tolliday N, Clemons PA, Ferraiolo P, et al. Small molecules, big players: the National Cancer Institute’s Initiative for Chemical Genetics. Cancer Res. 2006;66(18):8935-42. doi:10.1158/0008-5472.CAN-06-2552
Chemical Biology and Therapeutics Science Program
Bradner JE, McPherson OM, Mazitschek R, et al. A robust small-molecule microarray platform for screening cell lysates. Chem Biol. 2006;13(5):493-504. doi:10.1016/j.chembiol.2006.03.004
Bradner JE, McPherson OM, Koehler AN. A method for the covalent capture and screening of diverse small molecules in a microarray format. Nat Protoc. 2006;1(5):2344-52. doi:10.1038/nprot.2006.282
Glasfeld A, Koehler AN, Schumacher MA, Brennan RG. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J Mol Biol. 1999;291(2):347-61. doi:10.1006/jmbi.1999.2946