Weidmann AG, Choudhary A. Special Issue on the Chemical Biology of CRISPR. ACS Chem Biol. 2018;13(2):283-284. doi:10.1021/acschembio.8b00134
Chemical Biology and Therapeutics Science Program
Eaton JK, Furst L, Ruberto RA, et al. Targeting a Therapy-Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors. bioRxiv. 2018. doi:10.1101/376764
Andrew AL, Perry BW, Card DC, et al. Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python. BMC Genomics. 2017;18(1):338. doi:10.1186/s12864-017-3743-1
Maji B, Moore CL, Zetsche B, et al. Multidimensional chemical control of CRISPR-Cas9. Nat Chem Biol. 2017;13(1):9-11. doi:10.1038/nchembio.2224
Chaikind B, Bessen JL, Thompson DB, Hu JH, Liu DR. A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells. Nucleic Acids Res. 2016;44(20):9758-9770. doi:10.1093/nar/gkw707
Kato N, Comer E, Sakata-Kato T, et al. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. 2016;538(7625):344-349. doi:10.1038/nature19804
Dirice E, Walpita D, Vetere A, et al. Inhibition of DYRK1A Stimulates Human β-Cell Proliferation. Diabetes. 2016;65(6):1660-71. doi:10.2337/db15-1127
Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature. 2016;533(7603):420-4. doi:10.1038/nature17946
Badran AH, Guzov VM, Huai Q, et al. Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance. Nature. 2016;533(7601):58-63. doi:10.1038/nature17938
Rees MG, Seashore-Ludlow B, Cheah JH, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016;12(2):109-16. doi:10.1038/nchembio.1986