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Chromatin-modifying enzymes as modulators of reprogramming. 1.Onder TT, Kara N, Cherry A, et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature. 2012;483(7391):598-602. doi:10.1038/nature10953. Read more
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. 1.Melnikov A, Murugan A, Zhang X, et al. Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nat Biotechnol. 2012;30(3):271-7. doi:10.1038/nbt.2137. Read more
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. 1.Grad YH, Lipsitch M, Feldgarden M, et al. Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. Proc Natl Acad Sci U S A. 2012;109(8):3065-70. doi:10.1073/pnas.1121491109. Read more
The mystery of missing heritability: Genetic interactions create phantom heritability. 1.Zuk O, Hechter E, Sunyaev SR, Lander ES. The mystery of missing heritability: Genetic interactions create phantom heritability. Proc Natl Acad Sci U S A. 2012;109(4):1193-8. doi:10.1073/pnas.1119675109. Read more
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. 1.Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26):2497-506. doi:10.1056/NEJMoa1109016. Read more
Detecting novel associations in large data sets. 1.Reshef DN, Reshef YA, Finucane HK, et al. Detecting novel associations in large data sets. Science. 2011;334(6062):1518-24. doi:10.1126/science.1205438. Read more
Chromosome substitution strains: a new way to study genetically complex traits. 1.Hill A, Lander ES, Nadeau J. Chromosome substitution strains: a new way to study genetically complex traits. Methods in molecular medicine. 2011;128:153-72. doi:10.1385/1-59745-159-2:153. Read more
The variant call format and VCFtools. 1.Danecek P, Auton A, Abecasis G, et al. The variant call format and VCFtools. Bioinformatics. 2011;27(15):2156-8. doi:10.1093/bioinformatics/btr330. Read more
Variation in genome-wide mutation rates within and between human families. 1.Conrad DF, Keebler JEM, DePristo MA, et al. Variation in genome-wide mutation rates within and between human families. Nat Genet. 2011;43(7):712-4. doi:10.1038/ng.862. Read more