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Publications

A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma.

Rade M, Fandrei D, Kreuz M, et al. A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma. Cancer cell. 2025. doi:10.1016/j.ccell.2025.10.014

Advancing CNS tumor diagnostics with expanded DNA methylation-based classification.

Sill M, Schrimpf D, Patel A, et al. Advancing CNS tumor diagnostics with expanded DNA methylation-based classification. Cancer cell. 2025. doi:10.1016/j.ccell.2025.11.002

Integrating single-cell biophysical and transcriptomic features to resolve functional heterogeneity in mantle cell lymphoma.

Zhang Y, Debaize L, Langenbucher A, et al. Integrating single-cell biophysical and transcriptomic features to resolve functional heterogeneity in mantle cell lymphoma. Science advances. 2025;11(49):eady2963. doi:10.1126/sciadv.ady2963

An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy.

Giadone RM, Holton KM, Hu X, et al. An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.11.04.686319

PMCID

PMC12637412

Adaptation of the multiplexed CRISPR-Cas13 CARMEN RVP assay for longitudinal detection of respiratory pathogens from air samples.

Ellis AL, Stauss M, Tiburcio PB, et al. Adaptation of the multiplexed CRISPR-Cas13 CARMEN RVP assay for longitudinal detection of respiratory pathogens from air samples. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.10.21.25338488

PMCID

PMC12633622

Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy.

Knight AD, Robitschek EJ, Lin JR, et al. Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.10.31.25338685

PMCID

PMC12637767

Biological aging and gout risk in hyperuricemia: a UK biobank cohort study.

Li N, Chen Z, Han M, et al. Biological aging and gout risk in hyperuricemia: a UK biobank cohort study. International journal of surgery (London, England). 2025. doi:10.1097/JS9.0000000000003948

Nonlinear Decline in the Association between Birth Weight and Cognitive Ability from Infancy to Midlife in a Community Sample of Twins.

Bell SA, Womack SR, Kam A, et al. Nonlinear Decline in the Association between Birth Weight and Cognitive Ability from Infancy to Midlife in a Community Sample of Twins. The journals of gerontology. Series B, Psychological sciences and social sciences. 2025. doi:10.1093/geronb/gbaf247

Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy.

Giovannoni F, Strathdee CA, Akl CF, et al. Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy. Nature cancer. 2025. doi:10.1038/s43018-025-01070-6

The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin.

Carlson ES, Haslecker R, Lecchi C, et al. The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin. Science (New York, N.Y.). 2025;390(6777):eady3571. doi:10.1126/science.ady3571