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Publications

Homo-PROTACs for the Chemical Knockdown of Cereblon.

Steinebach C, Lindner S, Udeshi ND, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018;13(9):2771-2782. doi:10.1021/acschembio.8b00693

Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65.

Hudry E, Andres-Mateos E, Lerner EP, et al. Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65. Mol Ther Methods Clin Dev. 2018;10:197-209. doi:10.1016/j.omtm.2018.07.006

Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform.

Pane K, Cafaro V, Avitabile A, et al. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. ACS Synth Biol. 2018;7(9):2105-2115. doi:10.1021/acssynbio.8b00084

Cellular checkpoint control using programmable sequential logic.

Andrews LB, Nielsen AAK, Voigt CA. Cellular checkpoint control using programmable sequential logic. Science. 2018;361(6408). doi:10.1126/science.aap8987

Engineered CRISPR-Cas9 nuclease with expanded targeting space.

Nishimasu H, Shi X, Ishiguro S, et al. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science. 2018;361(6408):1259-1262. doi:10.1126/science.aas9129

Targeted therapy for fusion-driven high-risk acute leukemia.

Pikman Y, Stegmaier K. Targeted therapy for fusion-driven high-risk acute leukemia. Blood. 2018;132(12):1241-1247. doi:10.1182/blood-2018-04-784157

Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4 activity.

Sievers QL, Gasser JA, Cowley GS, Fischer ES, Ebert BL. Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4 activity. Blood. 2018;132(12):1293-1303. doi:10.1182/blood-2018-01-821769

Publisher Correction: Ancient DNA from Chalcolithic Israel reveals the role of population mixture in cultural transformation.

Harney E, May H, Shalem D, et al. Publisher Correction: Ancient DNA from Chalcolithic Israel reveals the role of population mixture in cultural transformation. Nat Commun. 2018;9(1):3913. doi:10.1038/s41467-018-06484-8

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.

McBrayer SK, Mayers JR, DiNatale GJ, et al. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. 2018;175(1):101-116.e25. doi:10.1016/j.cell.2018.08.038

Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds.

Melillo B, Zoller J, Hua BK, et al. Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds. J Am Chem Soc. 2018;140(37):11784-11790. doi:10.1021/jacs.8b07319