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Publications

Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.

Long JD, Lee JM, Aylward EH, et al. Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase. Am J Hum Genet. 2018;103(3):349-357. doi:10.1016/j.ajhg.2018.07.017

A case of mistaken identity.

Hanna RE, Doench JG. A case of mistaken identity. Nat Biotechnol. 2018;36(9):802-804. doi:10.1038/nbt.4208

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.

Xu D, Jin T, Zhu H, et al. TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. 2018;174(6):1477-1491.e19. doi:10.1016/j.cell.2018.07.041

Breaking and Sealing Barriers in Retinal Gene Therapy.

Miller JW, Vandenberghe LH. Breaking and Sealing Barriers in Retinal Gene Therapy. Mol Ther. 2018;26(9):2081-2082. doi:10.1016/j.ymthe.2018.08.003

Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells.

Darnell M, O’Neil A, Mao A, Gu L, Rubin LL, Mooney DJ. Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells. Proc Natl Acad Sci U S A. 2018;115(36):E8368-E8377. doi:10.1073/pnas.1802568115

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, et al. Genotype-targeted local therapy of glioma. Proc Natl Acad Sci U S A. 2018;115(36):E8388-E8394. doi:10.1073/pnas.1805751115

Classification of prostate cancer using a protease activity nanosensor library.

Dudani JS, Ibrahim M, Kirkpatrick J, Warren AD, Bhatia SN. Classification of prostate cancer using a protease activity nanosensor library. Proc Natl Acad Sci U S A. 2018;115(36):8954-8959. doi:10.1073/pnas.1805337115

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.

Early JO, Menon D, Wyse CA, et al. Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2. Proc Natl Acad Sci U S A. 2018;115(36):E8460-E8468. doi:10.1073/pnas.1800431115

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq.

Karaayvaz M, Cristea S, Gillespie SM, et al. Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq. Nat Commun. 2018;9(1):3588. doi:10.1038/s41467-018-06052-0

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity.

Frank SR, Köllmann CP, Luong P, et al. p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity. J Cell Biol. 2018;217(9):3183-3201. doi:10.1083/jcb.201710058