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Publications

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors.

Villani AC, Satija R, Reynolds G, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356(6335). doi:10.1126/science.aah4573

Macrophages Facilitate Electrical Conduction in the Heart.

Hulsmans M, Clauss S, Xiao L, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169(3):510-522.e20. doi:10.1016/j.cell.2017.03.050

Virus genomes reveal factors that spread and sustained the Ebola epidemic.

Dudas G, Carvalho LM, Bedford T, et al. Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature. 2017;544(7650):309-315. doi:10.1038/nature22040

Improving genetic diagnosis in Mendelian disease with transcriptome sequencing.

Cummings BB, Marshall JL, Tukiainen T, et al. Improving genetic diagnosis in Mendelian disease with transcriptome sequencing. Sci Transl Med. 2017;9(386). doi:10.1126/scitranslmed.aal5209

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden.

Chalmers ZR, Connelly CF, Fabrizio D, et al. Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. Genome Med. 2017;9(1):34. doi:10.1186/s13073-017-0424-2

High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations.

Ndiaye YD, Diedhiou CK, Bei AK, et al. High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations. Malar J. 2017;16(1):153. doi:10.1186/s12936-017-1811-2

Designing Hydrogels for On-Demand Therapy.

Oliva N, Conde J, Wang K, Artzi N. Designing Hydrogels for On-Demand Therapy. Acc Chem Res. 2017;50(4):669-679. doi:10.1021/acs.accounts.6b00536

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI).

Chen C, Xing D, Tan L, et al. Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI). Science. 2017;356(6334):189-194. doi:10.1126/science.aak9787

Discovery of Antimalarial Azetidine-2-carbonitriles That InhibitDihydroorotate Dehydrogenase.

Maetani M, Kato N, Jabor VAP, et al. Discovery of Antimalarial Azetidine-2-carbonitriles That InhibitDihydroorotate Dehydrogenase. ACS Med Chem Lett. 2017;8(4):438-442. doi:10.1021/acsmedchemlett.7b00030

Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.

Saleheen D, Natarajan P, Armean IM, et al. Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity. Nature. 2017;544(7649):235-239. doi:10.1038/nature22034