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Publications

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.

Yamada M, Watanabe Y, Gootenberg JS, et al. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems. Mol Cell. 2017;65(6):1109-1121.e3. doi:10.1016/j.molcel.2017.02.007

Clinical laboratories collaborate to resolve differences in variant interpretations submitted to ClinVar.

Harrison SM, Dolinsky JS, Johnson AEK, et al. Clinical laboratories collaborate to resolve differences in variant interpretations submitted to ClinVar. Genet Med. 2017. doi:10.1038/gim.2017.14

Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells.

Han S, Udeshi ND, Deerinck TJ, et al. Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells. Cell Chem Biol. 2017;24(3):404-414. doi:10.1016/j.chembiol.2017.02.002

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

Wolfson RL, Chantranupong L, Wyant GA, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543(7645):438-442. doi:10.1038/nature21423

3D hydrogel scaffold doped with 2D graphene materials for biosensors and bioelectronics.

Song HS, Kwon OS, Kim JH, Conde J, Artzi N. 3D hydrogel scaffold doped with 2D graphene materials for biosensors and bioelectronics. Biosens Bioelectron. 2017;89(Pt 1):187-200. doi:10.1016/j.bios.2016.03.045

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer.

Gallenne T, Ross KN, Visser NL, et al. Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer. Oncotarget. 2017;8(13):20572-20587. doi:10.18632/oncotarget.16244

Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort.

Emdin CA, Khera AV, Natarajan P, et al. Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort. Am J Cardiol. 2017;119(6):881-885. doi:10.1016/j.amjcard.2016.11.042

Is Coronary Atherosclerosis One Disease or Many? Setting Realistic Expectations for Precision Medicine.

Khera AV, Kathiresan S. Is Coronary Atherosclerosis One Disease or Many? Setting Realistic Expectations for Precision Medicine. Circulation. 2017;135(11):1005-1007. doi:10.1161/CIRCULATIONAHA.116.026479

CSF GABA is reduced in first-episode psychosis and associates to symptom severity.

Orhan F, Fatouros-Bergman H, Goiny M, et al. CSF GABA is reduced in first-episode psychosis and associates to symptom severity. Mol Psychiatry. 2017. doi:10.1038/mp.2017.25

Science Signaling Podcast for 14 March 2017: The Cancer Moonshot.

Yaffe MB, VanHook AM. Science Signaling Podcast for 14 March 2017: The Cancer Moonshot. Sci Signal. 2017;10(470). doi:10.1126/scisignal.aan1418