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Publications

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.

Cheng CW, Villani V, Buono R, et al. Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. Cell. 2017;168(5):775-788.e12. doi:10.1016/j.cell.2017.01.040

SnapShot: Class 1 CRISPR-Cas Systems.

Makarova KS, Zhang F, Koonin EV. SnapShot: Class 1 CRISPR-Cas Systems. Cell. 2017;168(5):946-946.e1. doi:10.1016/j.cell.2017.02.018

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

Wang T, Yu H, Hughes NW, et al. Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. Cell. 2017;168(5):890-903.e15. doi:10.1016/j.cell.2017.01.013

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, et al. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst. 2017;4(2):157-170.e14. doi:10.1016/j.cels.2016.12.011

In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.

Chung CY, Khurana V, Yi S, et al. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Syst. 2017;4(2):242-250.e4. doi:10.1016/j.cels.2017.01.002

Predicting gene expression in massively parallel reporter assays: A comparative study.

Kreimer A, Zeng H, Edwards MD, et al. Predicting gene expression in massively parallel reporter assays: A comparative study. Hum Mutat. 2017. doi:10.1002/humu.23197

Archaeogenomic evidence reveals prehistoric matrilineal dynasty.

Kennett DJ, Plog S, George RJ, et al. Archaeogenomic evidence reveals prehistoric matrilineal dynasty. Nat Commun. 2017;8:14115. doi:10.1038/ncomms14115

Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers.

Thomas C, Henry W, Cuiffo BG, et al. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Sci Signal. 2017;10(467). doi:10.1126/scisignal.aah4674

Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer.

Karnoub AE, VanHook AM. Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer. Sci Signal. 2017;10(467). doi:10.1126/scisignal.aam8855

SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity.

Ioris RM, Galié M, Ramadori G, et al. SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity. Cell Rep. 2017;18(8):1858-1868. doi:10.1016/j.celrep.2017.01.065