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Publications

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer.

Gallenne T, Ross KN, Visser NL, et al. Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer. Oncotarget. 2017;8(13):20572-20587. doi:10.18632/oncotarget.16244

Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort.

Emdin CA, Khera AV, Natarajan P, et al. Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort. Am J Cardiol. 2017;119(6):881-885. doi:10.1016/j.amjcard.2016.11.042

Is Coronary Atherosclerosis One Disease or Many? Setting Realistic Expectations for Precision Medicine.

Khera AV, Kathiresan S. Is Coronary Atherosclerosis One Disease or Many? Setting Realistic Expectations for Precision Medicine. Circulation. 2017;135(11):1005-1007. doi:10.1161/CIRCULATIONAHA.116.026479

CSF GABA is reduced in first-episode psychosis and associates to symptom severity.

Orhan F, Fatouros-Bergman H, Goiny M, et al. CSF GABA is reduced in first-episode psychosis and associates to symptom severity. Mol Psychiatry. 2017. doi:10.1038/mp.2017.25

Science Signaling Podcast for 14 March 2017: The Cancer Moonshot.

Yaffe MB, VanHook AM. Science Signaling Podcast for 14 March 2017: The Cancer Moonshot. Sci Signal. 2017;10(470). doi:10.1126/scisignal.aan1418

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.

Farshidfar F, Zheng S, Gingras MC, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Rep. 2017;18(11):2780-2794. doi:10.1016/j.celrep.2017.02.033

Integrated Molecular Characterization of Uterine Carcinosarcoma.

Cherniack AD, Shen H, Walter V, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31(3):411-423. doi:10.1016/j.ccell.2017.02.010

Imaging mass spectrometry demonstrates age-related decline in human adipose plasticity.

Guillermier C, Fazeli PK, Kim S, et al. Imaging mass spectrometry demonstrates age-related decline in human adipose plasticity. JCI Insight. 2017;2(5):e90349. doi:10.1172/jci.insight.90349

Elucidation of MRAS-mediated Noonan syndrome with cardiac hypertrophy.

Higgins EM, Bos M, Mason-Suares H, et al. Elucidation of MRAS-mediated Noonan syndrome with cardiac hypertrophy. JCI Insight. 2017;2(5):e91225. doi:10.1172/jci.insight.91225

Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation.

Kim AR, Ulirsch JC, Wilmes S, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 2017;168(6):1053-1064.e15. doi:10.1016/j.cell.2017.02.026