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Publications

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.

Botella L, Vaubourgeix J, Livny J, Schnappinger D. Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Nat Commun. 2017;8:14731. doi:10.1038/ncomms14731

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.

Huang K lin, Li S, Mertins P, et al. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017;8:14864. doi:10.1038/ncomms14864

Genetic effects influencing risk for major depressive disorder in China and Europe.

Bigdeli TB, Ripke S, Peterson RE, et al. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry. 2017;7(3):e1074. doi:10.1038/tp.2016.292

Neuroprotective Functions for the Histone Deacetylase SIRT6.

Kaluski S, Portillo M, Besnard A, et al. Neuroprotective Functions for the Histone Deacetylase SIRT6. Cell Rep. 2017;18(13):3052-3062. doi:10.1016/j.celrep.2017.03.008

A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.

Zhou J, Tien AC, Alberta JA, et al. A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2. Cell Rep. 2017;18(13):3167-3177. doi:10.1016/j.celrep.2017.03.003

Prenatal DNA Sequencing: Clinical, Counseling, and Diagnostic Laboratory Considerations.

Tayoun ANA, Spinner NB, Rehm HL, Green RC, Bianchi DW. Prenatal DNA Sequencing: Clinical, Counseling, and Diagnostic Laboratory Considerations. Prenat Diagn. 2017. doi:10.1002/pd.5038

Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.

Sharabi K, Lin H, Tavares CDJ, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017;169(1):148-160.e15. doi:10.1016/j.cell.2017.03.001

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.

Manolio TA, Fowler DM, Starita LM, et al. Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research. Cell. 2017;169(1):6-12. doi:10.1016/j.cell.2017.03.005

Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections.

Schreiber HL, Conover MS, Chou WC, et al. Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections. Sci Transl Med. 2017;9(382). doi:10.1126/scitranslmed.aaf1283

Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.

Chibnik LB, White CC, Mukherjee S, et al. Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2017. doi:10.1038/mp.2017.20