Publications

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.

Fishbein L, Leshchiner I, Walter V, et al. Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma. Cancer Cell. 2017;31(2):181-193. doi:10.1016/j.ccell.2017.01.001

A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline.

Levin BJ, Huang YY, Peck SC, et al. A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline. Science. 2017;355(6325). doi:10.1126/science.aai8386

Comparative Analysis Highlights Variable Genome Content of Wheat Rusts and Divergence of the Mating Loci.

Cuomo CA, Bakkeren G, Khalil HB, et al. Comparative Analysis Highlights Variable Genome Content of Wheat Rusts and Divergence of the Mating Loci. G3 (Bethesda). 2017;7(2):361-376. doi:10.1534/g3.116.032797

Rare and low-frequency coding variants alter human adult height.

Marouli E, Graff M, Medina-Gomez C, et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017;542(7640):186-190. doi:10.1038/nature21039

Shared genetic variants suggest common pathways in allergy and autoimmune diseases.

Kreiner E, Waage J, Standl M, et al. Shared genetic variants suggest common pathways in allergy and autoimmune diseases. J Allergy Clin Immunol. 2017. doi:10.1016/j.jaci.2016.10.055

Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.

Paolella BR, Gibson WJ, Urbanski LM, et al. Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability. Elife. 2017;6. doi:10.7554/eLife.23268

Transethnic genome-wide scan identifies novel Alzheimer's disease loci.

Jun GR, Chung J, Mez J, et al. Transethnic genome-wide scan identifies novel Alzheimer’s disease loci. Alzheimers Dement. 2017. doi:10.1016/j.jalz.2016.12.012

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

Wang B, Krall EB, Aguirre AJ, et al. ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition. Cell Rep. 2017;18(6):1543-1557. doi:10.1016/j.celrep.2017.01.031

Towards a Global Cancer Knowledge Network: Dissecting the current international cancer genomic sequencing landscape.

Vis DJ, Lewin J, Liao RG, et al. Towards a Global Cancer Knowledge Network: Dissecting the current international cancer genomic sequencing landscape. Ann Oncol. 2017. doi:10.1093/annonc/mdx037

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.

Huang JH, Park H, Iaconelli J, et al. Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. J Proteome Res. 2017;16(2):481-493. doi:10.1021/acs.jproteome.6b00628